ArticleInternational ophthalmology2021
Prevalence of primary open-angle glaucoma in a Somalia population.
Article in International ophthalmology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- CRISPR-CasRx-mediated disruption of Aqp1/Adrb2/Rock1/Rock2 genes reduces intraocular pressure and retinal ganglion cell damage in mice.Nature communications · 2024Article
- Elevated Levels of Growth/Differentiation Factor-15 in the Aqueous Humor and Serum of Glaucoma Patients.Journal of clinical medicine · 2022Article
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Authors and funding
3 authors.
Funding
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Abstract
purposeTo determine the prevalence of primary open-angle glaucoma (POAG) in patients over 40 years that presented to our tertiary hospital in Somalia Mogadishu.
methodsThis prospective cross-sectional study included 1550 patients older than 40 years that presented to the ophthalmology clinic of Somalia Mogadishu - Turkey Training and Research Hospital. The patients were evaluated in terms of age, gender, intraocular pressure, and optical cup/disk (C/D) ratio, and central corneal thickness measurements were taken.
resultsThe prevalence of glaucoma in the study population over the age of 40 years was 7%. The prevalence of glaucoma was 40% in the 40-50-year group, 6.8% in the 50-60-year group, 7% in the 60-70-year group, 9.9% in the 70-80-year group, and 12.3% in the 80-90-year group. The prevalence of glaucoma statistically significantly increased with advancing age (p < 0.001). The mean intraocular pressure was measured as 16.7 ± 3.3 mmHg for the overall patient population, 16.3 ± 2.9 mmHg for the female patients, and 17.1 ± 3.1 mmHg for the male patients. The mean intraocular pressure of the patients diagnosed with POAG was 27.3 ± 4.2 mmHg, and their mean corneal thickness was 507.9 µm, which was significantly lower than the value of the patients without POAG (545.8) (p < 0.001). The mean C/D ratio was calculated as 0.56 ± 0.21 for the patients with POAG and general 0.24 ± 0.16 for the overall patient population, indicating a statistically significant difference (p < 0.001).
conclusionsA high rate of POAG is seen in patients over 40 years of age in Somalia. The mechanism underlying POAG needs to be investigated in this population.
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