Evidence map›Paper›PMID 33057779›Full record

ArticleNaunyn-Schmiedeberg's archives of pharmacology2021

Galactomannan of Delonix regia seeds reduces nociception and morphological damage in the rat model of osteoarthritis induced by sodium monoiodoacetate.

Francisco Glerison da Silva Nascimento, Pedro Henrique de Souza Ferreira Bringel, Francisco Wildson Silva Maia, Carlos Pinheiro Chagas Lima, Rômulo Couto Alves, Judith Pessoa Andrade Feitosa, Mário Rogério Lima Mota, Ana Maria Sampaio Assreuy, Rondinelle Ribeiro Castro

Abstract read
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In one paragraph

Article in Naunyn-Schmiedeberg's archives of pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Francisco Glerison da Silva NascimentoSuperior Institute of Biomedical Sciences, State University of Ceará, Av. Dr. Silas Munguba, 1700, Fortaleza, CE, 60714-903, Brazil.ORCID https://orcid.org/0000-0003-2481-5733
Pedro Henrique de Souza Ferreira BringelSuperior Institute of Biomedical Sciences, State University of Ceará, Av. Dr. Silas Munguba, 1700, Fortaleza, CE, 60714-903, Brazil.ORCID https://orcid.org/0000-0001-6278-2755
Francisco Wildson Silva MaiaSuperior Institute of Biomedical Sciences, State University of Ceará, Av. Dr. Silas Munguba, 1700, Fortaleza, CE, 60714-903, Brazil.ORCID https://orcid.org/0000-0001-7336-6773
Carlos Pinheiro Chagas LimaDepartment of Organic and Inorganic Chemistry, Federal University of Ceará, Av. Mister Hull, s/n, Fortaleza, CE, 60451-970, Brazil.ORCID https://orcid.org/0000-0001-9539-9840
Rômulo Couto AlvesCatarinian Federal Institute of Education, Science and Technology, R. Vigário Frei João, 550, Luzerna, SC, 89609-000, Brazil.ORCID https://orcid.org/0000-0003-4680-5317
Judith Pessoa Andrade FeitosaDepartment of Organic and Inorganic Chemistry, Federal University of Ceará, Av. Mister Hull, s/n, Fortaleza, CE, 60451-970, Brazil.ORCID https://orcid.org/0000-0002-4466-0452
Mário Rogério Lima MotaDepartment of Dental Clinic, Faculty of Pharmacy, Dentistry and Nursing, Federal University of Ceará, Street Alexandre Baraúna, 949, Fortaleza, CE, 60430-160, Brazil.ORCID https://orcid.org/0000-0003-3778-0584
Ana Maria Sampaio AssreuySuperior Institute of Biomedical Sciences, State University of Ceará, Av. Dr. Silas Munguba, 1700, Fortaleza, CE, 60714-903, Brazil.ORCID https://orcid.org/0000-0002-2323-5385
Rondinelle Ribeiro CastroSuperior Institute of Biomedical Sciences, State University of Ceará, Av. Dr. Silas Munguba, 1700, Fortaleza, CE, 60714-903, Brazil. rondinelle.castro@uece.br.ORCID https://orcid.org/0000-0002-9399-4109
Universidade Estadual do Ceará · BRUniversidade Federal do Ceará · BRInstituto Federal Catarinense · BR

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 308433/2017-3Fundação Cearense de Apoio ao Desenvolvimento Científico e Tecnológico BPI-0031-00044.01.04/11
6 · The paper itself

Abstract

This study investigated the effects of the protein-free galactomannan obtained from Delonix regia seeds (GM-DR) in an experimental osteoarthritis (OA) model. GM-DR was obtained from water-homogenized endosperms by collection of the supernatant and precipitation with ethanol. The remaining proteins in the galactomannan were removed by alkaline hydrolysis. Weight average molar mass (M

Indexed as

AnalgesicsAnimalsDisease Models, AnimalFabaceaeFoot JointsGalactoseIodoacetic AcidMaleMannansNociceptionOsteoarthritisPainRatsRats, WistarSeedsAnalgesicsgalactomannanGalactoseIodoacetic AcidMannansDelonix regiaGalactomannanHypernociception,·InflammationOsteoarthritisSodium monoiodoacetete

Identifiers

PMID33057779
OpenAlexW3092834480

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.