Evidence map›Paper›PMID 33057739›Full record

Trial reportInternational urogynecology journal2021

Transcutaneous tibial nerve stimulation to treat urgency urinary incontinence in older women: 12-month follow-up of a randomized controlled trial.

Lucas Schreiner, Christiana Campani Nygaard, Thais Guimarães Dos Santos, Mara Regina Knorst, Irênio Gomes da Silva Filho

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in International urogynecology journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05309993 (INvestigation of TENS Efficacy Versus Posterior Tibial Nerve Stimulation for Overactive Bladder), which is not on this map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05309993 naterminatednot on this mapstarted 2022, after this paper: background citation

INvestigation of TENS Efficacy Versus Posterior Tibial Nerve Stimulation for Overactive Bladder

TypeinterventionalSponsorUniversity of New MexicoRan2022 to 2025Enrolled27ConditionsOveractive Bladder, Overactive Bladder Syndrome, Urinary Urge Incontinence, Urinary Bladder, OveractiveArmsPTNS, TENS
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Lucas SchreinerGynecology Department, Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, Brazil.
Christiana Campani NygaardGynecology Department, Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, Brazil. cnygcnyg@gmail.com.ORCID http://orcid.org/0000-0003-4545-3671
Thais Guimarães Dos SantosGynecology Department, Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, Brazil.
Mara Regina KnorstGynecology Department, Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, Brazil.
Irênio Gomes da Silva FilhoNeurology Department, Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, Brazil.
Pontifícia Universidade Católica do Rio Grande do Sul · BREpsom and St Helier University Hospitals NHS Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introduction and hypothesisUrgency urinary incontinence (UUI) is highly prevalent in elderly individuals and has a great impact on quality of life. Transcutaneous tibial nerve stimulation (TTNS) can be an effective treatment option for UUI in older women.

methodsThis is a single-center randomized clinical trial with a 12-month follow-up involving 106 women > 60 years of age. Kegel exercises and bladder retraining were performed alone or in combination with TTNS, which consisted of using a transcutaneous electrical nerve stimulator for 30 min once a week for 12 weeks with the following settings: continuous mode, 10 Hz, 200 ms, and 10 to 50 mA (according to hallux mobilization). Responders to therapy who experienced failure during follow-up were invited for a 3-week protocol with the same parameters as those used for the initial therapy. Patients were evaluated at baseline, 4 weeks after the 12-week protocol, and every 3 months for 12 months, through subjective satisfaction questionnaires, a 3-day bladder diary and the International Consultation on Incontinence Questionnaire-Short Form. King's Health Questionnaire was applied pretreatment and 4 weeks after the last session of the 12-week protocol.

resultsA total of 101 women completed the initial 12-week protocol. TTNS patients reported 66.7% subjective global satisfaction vs. 32.0% in the control group (p < 0.001). The TTNS group showed statistically significant improvement in quality of life (QoL) and UUI parameters compared with the control group. Forty-eight patients were satisfied after the 12-week protocol and completed the 12-month follow-up (32 in the TTNS group and 16 in the control group). A total of 80.5% of responders to TTNS were still satisfied at the end of the 12-month follow-up vs. 30.8% in the control group (p = 0.009).

conclusionTTNS is effective at the 12-month follow-up for the treatment of UUI in elderly women.

Indexed as

Transcutaneous Electric Nerve StimulationUrinary Bladder, OveractiveUrinary IncontinenceAgedFemaleFollow-Up StudiesHumansQuality of LifeTibial NerveTreatment OutcomeElderlyElectrical stimulationUrgency urinary incontinence

Identifiers

PMID33057739
OpenAlexW3092796492

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.