Evidence map›Paper›PMID 33057636›Full record

ArticleThe Journal of cell biology2020

"Neur"al brain wave: Coordinating epithelial-to-neural stem cell transition in the fly optic lobe.

Arnaud Ambrosini, Katja Röper

Abstract readComment
In one paragraph

Article in The Journal of cell biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Arnaud AmbrosiniMedical Research Council Laboratory of Molecular Biology, Cambridge Biomedical Campus, Cambridge, UK.
Katja RöperMedical Research Council Laboratory of Molecular Biology, Cambridge Biomedical Campus, Cambridge, UK.

Funding

Medical Research Council MC_UP_1201/11Medical Research Council U105178780
6 · The paper itself

Abstract

In the Drosophila larval optic lobe, the generation of neural stem cells involves an epithelial-to-mesenchymal-like transition of a continuous stripe of cells that sweeps across the neuroepithelium, but the dynamics at cell and tissue level were unknown until now. In this issue, Shard et al. (2020. J. Cell Biol.https://doi.org/10.1083/jcb.202005035) identify that Neuralized controls a partial epithelial-to-mesenchymal transition through regulation of the apical Crumbs complex and through the coordination of cell behaviors such as apical constriction and cell alignment.

Indexed as

Brain WavesDrosophila ProteinsNeural Stem CellsAnimalsDrosophilaEpitheliumDrosophila Proteins

Identifiers

PMID33057636
PMCPMC7568446

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.