Evidence map›Paper›PMID 33057444›Full record

ArticlePloS one2020

Implementation planning for community-based point-of-care HIV testing for infants: Recommendations from community leaders in Kenya.

Lynton W Macharia, Catherine Wexler, Melinda Brown, May Maloba, Ruby Angeline Pricilla, Natabhona M Mabachi, Elizabeth Muchoki, Shadrack Babu, Martin Ochieng, Brad Gautney and 2 more

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.1field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 3 countries.

Lynton W MachariaDepartment of Family Medicine, University of Kansas Medical Center, Kansas City, KS, United States of America.
Catherine WexlerDepartment of Family Medicine, University of Kansas Medical Center, Kansas City, KS, United States of America.ORCID 0000-0003-1891-9165
Melinda BrownDepartment of Family Medicine, University of Kansas Medical Center, Kansas City, KS, United States of America.ORCID 0000-0002-9555-5804
May MalobaGlobal Health Innovations, Nairobi, Kenya.
Ruby Angeline PricillaChristian Medical College, Vellore, Tamil Nadu, India.
Natabhona M MabachiDepartment of Family Medicine, University of Kansas Medical Center, Kansas City, KS, United States of America.
Elizabeth MuchokiKenya Medical Research Institute, Nairobi, Kenya.
Shadrack BabuKenya Medical Research Institute, Nairobi, Kenya.
Martin OchiengKenya Medical Research Institute, Nairobi, Kenya.
Brad GautneyGlobal Health Innovations, Dallas, TX, United States of America.
Kathy GogginHealth Services and Outcomes Research, Children's Mercy Hospitals and Clinics, Kansas City, MO, United States of America.
Sarah Finocchario-KesslerDepartment of Family Medicine, University of Kansas Medical Center, Kansas City, KS, United States of America.
University of Kansas Medical Center · USKenya Medical Research Institute · KEChildren's Mercy Hospital · USChristian Medical College, Vellore · INHealth Innovations (United States) · US

Funding

Piloting at-birth point of care HIV testing strategies in KenyaR01HD076673 · NICHD · UNIVERSITY OF KANSAS MEDICAL CENTER · PI KESSLER, SARAH FINOCCHARIO · 2013 to 2017
$3.4M
NICHD NIH HHS R01 HD076673
6 · The paper itself

Abstract

backgroundEarly infant diagnosis (EID) establishes the presence of HIV infection in HIV-exposed infants and children younger than 18 months of age. EID services are hospital-based, and thus fail to capture HIV-exposed infants who are not brought to the hospital for care. Point-of-care (POC) diagnostic systems deployed in the community could increase the proportion tested and linked to treatment, but little feasibility and acceptability data is available.

methodsSemi-structured interviews (n = 74) were conducted by a Kenyan team with community members (Community Health Workers/Volunteers [CHW/CHV], Traditional Birth Attendants [TBAs], community leaders) and parents of HIV-exposed infants at four study sites in Kenya to elicit feedback on the acceptability and feasibility of community-based POC HIV testing.

resultsParticipants described existing community health resources that could be leveraged to support integration of community-based POC HIV testing; however, the added demand placed on CHW/CHV could pose a challenge. Participants indicated that other potential barriers (concerns about confidentiality, disclosure, and HIV stigma) could be overcome with strong engagement from trusted community leaders and health providers, community sensitization, and strategic location and timing of testing. These steps were seen to improve acceptability and maximize the recognized benefits (rapid results, improved reach) of community-based testing.

conclusionCommunity members felt that with strategic planning and engagement, community-based POC HIV testing could be a feasible and acceptable strategy to overcome the existing barriers of hospital-based EID.

Indexed as

Health Plan ImplementationSocial SupportEarly DiagnosisFemaleHIVHIV InfectionsHumansInfantInfectious Disease Transmission, VerticalKenyaMaleParentsPoint-of-Care SystemsPoint-of-Care TestingPostnatal Care

Identifiers

PMID33057444
PMCPMC7561120
OpenAlexW3092810443

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.