Evidence map›Paper›PMID 33057203›Full record

ReviewNature reviews. Microbiology2021

Considerations for diagnostic COVID-19 tests.

Olivier Vandenberg, Delphine Martiny, Olivier Rochas, Alex van Belkum, Zisis Kozlakidis

Abstract readReview
In one paragraph

Review in Nature reviews. Microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 419 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
419citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

419 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Methicillin-ResistantMicroorganisms · 2026
    Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Review
  19. Article
  20. Observational

359 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Olivier VandenbergInnovation and Business Development Unit, Laboratoire Hospitalier Universtaire de Bruxelles - Universitair Laboratorium Brussel, Université Libre de Bruxelles, Brussels, Belgium. olivier.vandenberg@lhub-ulb.be.
Delphine MartinyDepartment of Microbiology, Laboratoire Hospitalier Universtaire de Bruxelles - Universitair Laboratorium Brussel, Université Libre de Bruxelles, Brussels, Belgium.
Olivier RochasStrategic Intelligence, Corporate Business Development, bioMérieux, Chemin de L'Orme, France.ORCID http://orcid.org/0000-0003-0940-5146
Alex van BelkumOpen Innovation and Partnerships, bioMérieux, La Balme Les Grottes, France. alex.vanbelkum@biomerieux.com.ORCID http://orcid.org/0000-0001-8545-5108
Zisis KozlakidisLaboratory Services and Biobank Group, International Agency for Research on Cancer, World Health Organization, Lyon, France.

Funding

World Health Organization 001
6 · The paper itself

Abstract

During the early phase of the coronavirus disease 2019 (COVID-19) pandemic, design, development, validation, verification and implementation of diagnostic tests were actively addressed by a large number of diagnostic test manufacturers. Hundreds of molecular tests and immunoassays were rapidly developed, albeit many still await clinical validation and formal approval. In this Review, we summarize the crucial role of diagnostic tests during the first global wave of COVID-19. We explore the technical and implementation problems encountered during this early phase in the pandemic, and try to define future directions for the progressive and better use of (syndromic) diagnostics during a possible resurgence of COVID-19 in future global waves or regional outbreaks. Continuous global improvement in diagnostic test preparedness is essential for more rapid detection of patients, possibly at the point of care, and for optimized prevention and treatment, in both industrialized countries and low-resource settings.

Indexed as

COVID-19 TestingCOVID-19Developed CountriesDeveloping CountriesDiagnostic Test ApprovalHumansManufacturing IndustryPandemicsPoint-of-Care TestingSARS-CoV-2Time FactorsWorld Health Organization

Identifiers

PMID33057203
PMCPMC7556561

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.