Evidence map›Paper›PMID 33057193›Full record

ArticleNature2020

The cellular basis of distinct thirst modalities.

Allan-Hermann Pool, Tongtong Wang, David A Stafford, Rebecca K Chance, Sangjun Lee, John Ngai, Yuki Oka

Open access · greenAbstract read
In one paragraph

Article in Nature, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers.

0numbers the graph read from it
0cells of the map it votes in
66citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

66 citing papers in PubMed, 94 citations in OpenAlex.

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  8. Modern Mining: The Role of Single-cell RNA Sequencing in Advancing Neuroscience Research.BioEssays : news and reviews in molecular, cellular and developmental biology · 2026
    Review
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  20. Body fluid regulation.Current opinion in neurobiology · 2025
    Review

6 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Allan-Hermann PoolDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA.
Tongtong WangDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA.ORCID http://orcid.org/0000-0002-0408-2571
David A StaffordDepartment of Molecular & Cell Biology, University of California, Berkeley, Berkeley, CA, USA.
Rebecca K ChanceDepartment of Molecular & Cell Biology, University of California, Berkeley, Berkeley, CA, USA.ORCID http://orcid.org/0000-0001-7059-6119
Sangjun LeeDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA.
John NgaiDepartment of Molecular & Cell Biology, University of California, Berkeley, Berkeley, CA, USA.
Yuki OkaDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA. yoka@caltech.edu.ORCID http://orcid.org/0000-0003-2686-0677
California Institute of Technology · USUniversity of California, Berkeley · USNational Institutes of Health · US

Funding

Generation of novel cell type specific mouse genetic toolsU19MH114830 · NIMH · ALLEN INSTITUTE · PI ZENG, HONGKUI · 2017 to 2021
$64.7M
Dissecting sodium appetite circuits in the mammalian brainR01NS123918 · NINDS · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI OKA, YUKI · 2021 to 2025
$2.0M
Neural circuits underlying thirst and satiety regulationR01NS109997 · NINDS · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI OKA, YUKI · 2018 to 2022
$1.9M
Genetic dissection of the neural circuits regulating appetiteR56MH113030 · NIMH · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI OKA, YUKI · 2017 to 2018
$825k
NIMH NIH HHS R56 MH113030NIMH NIH HHS U19 MH114830NINDS NIH HHS R01 NS109997NINDS NIH HHS R01 NS123918
6 · The paper itself

Abstract

Fluid intake is an essential innate behaviour that is mainly caused by two distinct types of thirst

Indexed as

AnimalsBase SequenceDrinkingFemaleHypovolemiaMaleMiceMice, Inbred C57BLModels, AnimalNeuronsOrganum VasculosumOsmotic PressureSingle-Cell AnalysisSubfornical OrganThirstWater Deprivation

Identifiers

PMID33057193
PMCPMC7718410
OpenAlexW3093167159

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.