Evidence map›Paper›PMID 33055231›Full record

ReviewClinical microbiology reviews2020

Remdesivir against COVID-19 and Other Viral Diseases.

Jakob J Malin, Isabelle Suárez, Vanessa Priesner, Gerd Fätkenheuer, Jan Rybniker

Open access · greenAbstract readReview
In one paragraph

Review in Clinical microbiology reviews, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 160 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
160citing papers in PubMed, 3 pooled it
5.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

160 citing papers in PubMed, 3 syntheses or guidelines pooled it, 292 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Remdesivir for the treatment of COVID-19.The Cochrane database of systematic reviews · 2021
    Pooled it
  4. Trial
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  17. Synthetic host defense peptide inhibits SARS-CoV-2 replicationAntimicrobial agents and chemotherapy · 2025
    Article
  18. Review
  19. Article
  20. Article

100 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jakob J MalinDepartment I of Internal Medicine, Division of Infectious Diseases, University of Cologne, Cologne, Germany jakob.malin@uk-koeln.de.ORCID 0000-0002-2989-0436
Isabelle SuárezDepartment I of Internal Medicine, Division of Infectious Diseases, University of Cologne, Cologne, Germany.
Vanessa PriesnerDepartment I of Internal Medicine, Division of Infectious Diseases, University of Cologne, Cologne, Germany.
Gerd FätkenheuerDepartment I of Internal Medicine, Division of Infectious Diseases, University of Cologne, Cologne, Germany.
Jan RybnikerDepartment I of Internal Medicine, Division of Infectious Diseases, University of Cologne, Cologne, Germany.
University of Cologne · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients and physicians worldwide are facing tremendous health care hazards that are caused by the ongoing severe acute respiratory distress syndrome coronavirus 2 (SARS-CoV-2) pandemic. Remdesivir (GS-5734) is the first approved treatment for severe coronavirus disease 2019 (COVID-19). It is a novel nucleoside analog with a broad antiviral activity spectrum among RNA viruses, including ebolavirus (EBOV) and the respiratory pathogens Middle East respiratory syndrome coronavirus (MERS-CoV), SARS-CoV, and SARS-CoV-2. First described in 2016, the drug was derived from an antiviral library of small molecules intended to target emerging pathogenic RNA viruses.

Indexed as

Adenosine MonophosphateAlanineAntiviral AgentsBetacoronavirusClinical Trials as TopicCompassionate Use TrialsCoronavirus InfectionsCOVID-19Drug Administration ScheduleEbolavirusHemorrhagic Fever, EbolaHumansMiddle East Respiratory Syndrome CoronavirusPandemicsPatient SafetyPneumonia, ViralAdenosine MonophosphateAlanineAntiviral AgentsremdesivirantiviralcoronavirusCOVID-19ebolavirusMERS-CoVremdesivirSARS-CoVSARS-CoV-2

Identifiers

PMID33055231
PMCPMC7566896
OpenAlexW3093244828

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.