Evidence map›Paper›PMID 33055213›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2020

The eukaryotic translation initiation factor eIF4E elevates steady-state m

Biljana Culjkovic-Kraljacic, Lucy Skrabanek, Maria V Revuelta, Jadwiga Gasiorek, Victoria H Cowling, Leandro Cerchietti, Katherine L B Borden

Open access · hybridAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 48 citations in OpenAlex.

  1. Trial
  2. A B1 SINE element within the mouseScience advances · 2026
    Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. Review
  14. Review
  15. Article
  16. Nuclear mRNA export.Acta biochimica et biophysica Sinica · 2024
    Review
  17. Review
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Biljana Culjkovic-KraljacicInstitute of Research in Immunology and Cancer, Department of Pathology and Cell Biology, Université de Montréal, Montréal, QC H3T 1J4, Canada.
Lucy SkrabanekApplied Bioinformatics Core, Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY 10065.ORCID 0000-0003-3720-4069
Maria V RevueltaDivision of Hematology & Medical Oncology, Department of Medicine, Weill Cornell Medicine, New York, NY 10065.ORCID 0000-0002-7922-0713
Jadwiga GasiorekInstitute of Research in Immunology and Cancer, Department of Pathology and Cell Biology, Université de Montréal, Montréal, QC H3T 1J4, Canada.ORCID 0000-0003-3363-7107
Victoria H CowlingCentre for Gene Regulation and Expression, School of Life Sciences, University of Dundee, Dundee DD1 5EH, United Kingdom.ORCID 0000-0001-7638-4870
Leandro CerchiettiDivision of Hematology & Medical Oncology, Department of Medicine, Weill Cornell Medicine, New York, NY 10065.ORCID 0000-0003-0608-1350
Katherine L B BordenInstitute of Research in Immunology and Cancer, Department of Pathology and Cell Biology, Université de Montréal, Montréal, QC H3T 1J4, Canada; katherine.borden@umontreal.ca.
Cornell University · USInstitute for Research in Immunology and Cancer · CAUniversity of Dundee · GB

Funding

PROMYELOCYTIC LEUKEMIA PROTEINS ROLE IN APOPTOSISR01CA080728 · NCI · UNIVERSITY OF MONTREAL · PI KATHERINE L B BORDEN · 1999 to 2026
$5.3M
Molecular Mechanisms of eIF4E Mediated TransformationR01CA098571 · NCI · UNIVERSITY OF MONTREAL · PI BORDEN, KATHERINE L B, GUZMAN, MONICA L · 2003 to 2025
$5.0M
Targeted Small Molecule Inhibitors for Inv(16) LeukemiaR01CA234478 · NCI · UNIVERSITY OF VIRGINIA · PI BUSHWELLER, JOHN HACKETT, CASTILLA, LUCIO H. · 2019 to 2023
$3.4M
Molecular Mechanisms of eIF4E mediated transformation.R56CA098571 · NCI · UNIVERSITY OF MONTREAL · PI BORDEN, KATHERINE L B · 2008 to 2008
$211k
Medical Research Council MR/K024213/1NCI NIH HHS R01 CA080728NCI NIH HHS R01 CA098571NCI NIH HHS R01 CA234478NCI NIH HHS R56 CA098571
6 · The paper itself

Abstract

Methyl-7-guanosine (m

Indexed as

Cell Line, TumorEukaryotic Initiation Factor-4EGuanosineHumansPolyribosomesRNA CapsRNA, MessengerTranscriptome8-methylguanosineEukaryotic Initiation Factor-4EGuanosineRNA CapsRNA, MessengereIF4Emethyl-7-guanosine capRNA cappingRNMT

Identifiers

PMID33055213
PMCPMC7604501
OpenAlexW3093426868

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.