ArticleeNeuro
The Dorsal Raphe Regulates the Duration of Attack through the Medial Orbitofrontal Cortex and Medial Amygdala.
Article in eNeuro. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Traumatic stress recruits an excitatory orbitofrontal-amygdala pathway to drive maladaptive aggression.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Article
- Lateral hypothalamus to dorsal raphe nucleus projections modulate intraspecific attack behavior in male mice.iScience · 2026Article
- Serotonin modulates nucleus accumbens circuits to suppress aggression in mice.Nature communications · 2026Article
- The Anterior BNST Is Required for Novelty-Driven Social Interaction.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Sex differences in the neural circuitry of aggression.bioRxiv : the preprint server for biology · 2025Article
- Serotonin modulates nucleus accumbens circuits to suppress aggression.bioRxiv : the preprint server for biology · 2025Article
- Familiarity Gates Socially Transmitted Aggression via the Medial Amygdala.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Dynamic changes of serotonin transporter expression in the prefrontal cortex evoked by aggressive social interactions.Neurobiology of stress · 2025Article
- Acute social defeat during adolescence promotes long-lasting aggression through activation of the medial amygdala.Frontiers in neuroscience · 2024Article
- A single dose of ketamine enhances early life stress-induced aggression with no effect on fear memory, anxiety-like behavior, or depression-like behavior in mice.Behavioral neuroscience · 2023Article
- Neurobiology of Aggression-Review of Recent Findings and Relationship with Alcohol and Trauma.Biology · 2023Review
- Visualizing traumatic stress-induced structural plasticity in a medial amygdala pathway using mGRASP.Frontiers in molecular neuroscience · 2023Article
- Deletion of the P/Q-Type Calcium Channel from Serotonergic Neurons Drives Male Aggression in Mice.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Article
- Lateral habenula glutamatergic neurons projecting to the dorsal raphe nucleus promote aggressive arousal in mice.Nature communications · 2022Article
- Opposing effects of NMDA receptor antagonists on early life stress-induced aggression in mice.Aggressive behavior · 2022Article
- Anger management: Mechanisms of glutamate receptor-mediated synaptic plasticity underlying animal aggression.The international journal of biochemistry & cell biology · 2022Review
- Neural circuit mechanisms that govern inter-male attack in mice.Cellular and molecular life sciences : CMLS · 2021Review
- Organization of neural circuits underlying social behavior: A consideration of the medial amygdala.Current opinion in neurobiology · 2021Review
- Sex-Specific Social Behavior and Amygdala Proteomic Deficits inFrontiers in behavioral neuroscience · 2021Article
- Human Primary Olfactory Amygdala Subregions Form Distinct Functional Networks, Suggesting Distinct Olfactory Functions.Frontiers in systems neuroscience · 2021Article
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2 authors.
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Abstract
The dorsal raphe (DR) is an evolutionarily conserved brain structure that is involved in aggressive behavior. It projects onto numerous cortical and limbic areas underlying attack behavior. The specific neurocircuit through which the DR regulates aggression, however, is largely unclear. In this study we show that DR neurons expressing CaMKIIα are activated by attack behavior in mice. These neurons project to the medial aspect of the orbitofrontal cortex (OFC; MeOC) and the medial amygdala (MeA), two key regions within the neural circuit known to control aggressive behavior. Using an
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