Evidence map›Paper›PMID 33054800›Full record

SynthesisBMC complementary medicine and therapies2020

A systematic review and meta-analysis of Liuzijue in stable patients with chronic obstructive pulmonary disease.

Lu Xiao, Hongxia Duan, Peijun Li, Weibing Wu, Chunlei Shan, Xiaodan Liu

Abstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in BMC complementary medicine and therapies, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Trial
  7. Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Breathing Exercises in the Treatment of COPD: An Overview of Systematic Reviews.International journal of chronic obstructive pulmonary disease · 2022
    Review
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lu XiaoSchool of Rehabilitation Science, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Hongxia DuanSchool of Rehabilitation Science, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Peijun LiDepartment of Sports Medicine, Shanghai University of Sport, Shanghai, China.
Weibing WuDepartment of Sports Medicine, Shanghai University of Sport, Shanghai, China.
Chunlei ShanSchool of Rehabilitation Science, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Xiaodan LiuSchool of Rehabilitation Science, Shanghai University of Traditional Chinese Medicine, Shanghai, China. hzhp403@126.com.

Funding

Health Qigong Administrative Center of the General Administration of Sport of China QG2019011National Natural Science Foundation of China 81902307
6 · The paper itself

Abstract

backgroundTo investigate the effectiveness of Liuzijue exercise on chronic obstructive pulmonary disease (COPD) in the stable phase.

methodsWe searched six electronic bibliographic databases (PubMed, EMBASE, The Cochrane Library, Web of Science, CNKI, and Wan Fang Data) from inception to August 2018. Randomized controlled trials (RCTs) were included if they evaluated the effect of Liuzijue exercise on stable COPD. Cochrane Collaboration risk-of-bias tool (Cochrane Handbook 5.1.0) was used to assess the risk of bias of included RCTs. Meta-analysis was performed using the Review Manager software (RevMan V.5.3.5) provided by the Cochrane Collaboration. Outcomes assessed included dyspnea, exercise capacity, lung function, and quality of life.

resultsFourteen RCTs involving 920 stable COPD patients were included in this systematic review and meta-analysis. The control groups received usual care. The average number of training sessions per participant was 9.3 per week, and the average length of these training sessions was 31.6 min per week. Training duration varied from 3 to 12 months. Meta-analysis results showed that Liuzijue exercise can effectively improve patients' Modified Medical Research Council Dyspnea Scale scores (MD = - 0.73, 95% CI: - 1.13 to - 0.33, P < 0.05), 6MWD (MD = 17.78, 95% CI: 7.97 to 27.58, P < 0.05), forced expiratory volume in one second (FEV

conclusionEvidence from meta-analysis suggested that Liuzijue exercise could improve dyspnea, exercise endurance, lung function, and quality of life for stable COPD patients. However, owing to the methodological bias and the placebo effect of Liuzijue exercise, there is a need for further research to confirm these findings.

trial registrationPROSPERO (ID: CRD42019130973 ).

Indexed as

Exercise TherapyExercise ToleranceHumansPulmonary Disease, Chronic ObstructiveQuality of LifeRandomized Controlled Trials as TopicRespiratory Function TestsChronic obstructive pulmonary diseaseExerciseLiuzijue

Identifiers

PMID33054800
PMCPMC7557061

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.