Evidence map›Paper›PMID 33054684›Full record

ArticleStatistical methods in medical research2021

Reference range: Which statistical intervals to use?

Wei Liu, Frank Bretz, Mario Cortina-Borja

Abstract read
In one paragraph

Article in Statistical methods in medical research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Wei LiuMathematical Sciences & Southampton Statistical Sciences Research Institute, University of Southampton, Southampton, UK.
Frank BretzNovartis Pharma AG, Basel, Switzerland.
Mario Cortina-BorjaDepartment of Population, Policy and Practice Research and Teaching, Great Ormond Street Institute of Child Health, University College London, London, UK.ORCID 0000-0003-0627-2624

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Reference ranges, which are data-based intervals aiming to contain a pre-specified large proportion of the population values, are powerful tools to analyse observations in clinical laboratories. Their main point is to classify any future observations from the population which fall outside them as atypical and thus may warrant further investigation. As a reference range is constructed from a random sample from the population, the event 'a reference range contains

Indexed as

Reference ValuesConfidence IntervalsProbabilitySample SizeNonparametric prediction intervalnonparametric tolerance intervalprediction intervalreference rangetolerance interval

Identifiers

PMID33054684
PMCPMC8008401

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.