Observational studyJournal of the American Heart Association2020
Association of the Amount and Pattern of Physical Activity With Arterial Stiffness: The Maastricht Study.
Observational study in Journal of the American Heart Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- The Conventional and Alternative Therapeutic Approaches in Arterial Stiffness Management.Pharmaceutics · 2026Review
- Association between frequency of meeting daily step thresholds and all-cause mortality and cardiovascular disease in older women.British journal of sports medicine · 2025Article
- Joint association of dietary index for gut microbiota and weekend warrior physical activity pattern with mortality among hypertensive patients.Nutrition & metabolism · 2025Article
- Not all steps are equal: independent prospective associations of stepping volume and patterns with incident type 2 diabetes mellitus in the Maastricht study.The international journal of behavioral nutrition and physical activity · 2025Article
- Cardiorespiratory Fitness as a Determinant of Arterial Elasticity in Response to Exercise: Evidence from a Study of Young Athletes and Healthy Controls.Acta Cardiologica Sinica · 2025Article
- Associations of cardiovascular health with arterial health in adults free of cardiovascular disease.American journal of preventive cardiology · 2025Article
- Accelerometer-derived "weekend warrior" physical activity pattern and cardiovascular disease in individuals with hypertension: a prospective cohort study.BMC medicine · 2025Article
- Arterial Stiffness in Heart-Healthy Indigenous Tsimane Forager-Horticulturalists.Journal of the American Heart Association · 2025Article
- Association of Accelerometer-Derived Physical Activity Pattern With the Risks of All-Cause, Cardiovascular Disease, and Cancer Death.Journal of the American Heart Association · 2025Article
- Arterial aging and the autonomic nervous system: is the relationship differently modified by physical activity in men and women?Frontiers in aging · 2025Article
- The association between weekend warrior physical activity pattern and albuminuria in hypertensive patients.BMC public health · 2024Article
- Estimated Pulse Wave Velocity Is Associated With a Higher Risk of Dementia in the Health and Retirement Study.American journal of hypertension · 2024Article
- Greater Adherence to Life's Essential 8 for Cardiovascular Health Is Associated With Lower Arterial Stiffness in Survivors of Cancer.Journal of the American Heart Association · 2024Article
- Functional capacity, physical activity, and arterial stiffness in patients with systemic sclerosis.Clinical rheumatology · 2024Article
- Article
- Relationship between objectively measured physical activity and subclinical cardiovascular disease: a systematic review.BMJ open sport & exercise medicine · 2024Article
- Meeting international self-report muscle strengthening guidelines is associated with better cardiovagal baroreflex sensitivity in adults.Frontiers in sports and active living · 2024Article
- Association of Accelerometer-Measured Sedentary Time and Physical Activity with Arterial Stiffness and Vascular Aging in the General Spanish Population, Analyzed by Sex.Reviews in cardiovascular medicine · 2023Article
- Observational
Corrections and comments
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Authors and funding
16 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background Arterial stiffness is an independent risk factor for cardiovascular disease and can be beneficially influenced by physical activity. However, it is not clear how an individual's physical activity pattern over a week is associated with arterial stiffness. Therefore, we examined the associations of the amount and pattern of higher intensity physical activity with arterial stiffness. Methods and Results Data from the Maastricht Study (n=1699; mean age: 60±8 years, 49.4% women, 26.9% type 2 diabetes mellitus) were used. Arterial stiffness was assessed by carotid-to-femoral pulse wave velocity and carotid distensibility. The amount (continuous variable as h/wk) and pattern (categorical variable) of higher intensity physical activity were assessed with the activPAL3. Activity groups were: inactive (<75 min/wk), insufficiently active (75-150 min/wk), weekend warrior (>150 min/wk in ≤2 sessions), and regularly active (>150 min/wk in ≥3 sessions). In the fully adjusted model (adjusted for demographic, lifestyle, and cardiovascular risk factors), higher intensity physical activity was associated with lower carotid-to-femoral pulse wave velocity (amount: β = -0.05, 95% CI, -0.09 to -0.01; insufficiently active: β = -0.33, 95% CI, -0.55 to -0.11; weekend warrior: β = -0.38, 95% CI, -0.64 to -0.12; and regularly active: β = -0.46, 95% CI, -0.71 to -0.21 [reference: inactive]). These associations were stronger in those with type 2 diabetes mellitus. There was no statistically significant association between higher intensity physical activity with carotid distensibility. Conclusions Participating in higher intensity physical activity was associated with lower carotid-to-femoral pulse wave velocity, but there was no difference between the regularly actives and the weekend warriors. From the perspective of arterial stiffness, engaging higher intensity physical activity, regardless of the weekly pattern, may be an important strategy to reduce the risk of cardiovascular disease, particularly in individuals with type 2 diabetes mellitus.
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