Evidence map›Paper›PMID 33054526›Full record

ArticleRNA biology2021

Translation of

Shihu Gan, Chao Su, Jinzheng Ma, Mingxia Liu, Xiaoteng Cui, Lingbiao Xin, Yuanyuan Ren, Xingjie Gao, Lin Ge, Minxin Wei and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in RNA biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Shihu GanDepartment of Biochemistry and Molecular Biology, School of Basic Medical Science, Tianjin Medical University, Tianjin, China.
Chao SuDepartment of Biochemistry and Molecular Biology, School of Basic Medical Science, Tianjin Medical University, Tianjin, China.
Jinzheng MaDepartment of Biochemistry and Molecular Biology, School of Basic Medical Science, Tianjin Medical University, Tianjin, China.
Mingxia LiuDepartment of Biochemistry and Molecular Biology, School of Basic Medical Science, Tianjin Medical University, Tianjin, China.
Xiaoteng CuiDepartment of Biochemistry and Molecular Biology, School of Basic Medical Science, Tianjin Medical University, Tianjin, China.ORCID 0000-0003-4994-147X
Lingbiao XinDepartment of Biochemistry and Molecular Biology, School of Basic Medical Science, Tianjin Medical University, Tianjin, China.
Yuanyuan RenDepartment of Biochemistry and Molecular Biology, School of Basic Medical Science, Tianjin Medical University, Tianjin, China.
Xingjie GaoDepartment of Biochemistry and Molecular Biology, School of Basic Medical Science, Tianjin Medical University, Tianjin, China.
Lin GeDepartment of Biochemistry and Molecular Biology, School of Basic Medical Science, Tianjin Medical University, Tianjin, China.
Minxin WeiDivision of Cardiac Surgery, Cardiovascular Medical Center, The University of Hong Kong-Shenzhen Hospital, Shenzhen, China.
Jie YangDepartment of Biochemistry and Molecular Biology, School of Basic Medical Science, Tianjin Medical University, Tianjin, China.
Tianjin Medical University · CNUniversity of Hong Kong - Shenzhen Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The mechanisms that regulate cell-cycle arrest of cardiomyocytes during heart development are largely unknown. We have previously identified Tudor staphylococcal nuclease (Tudor-SN) as a cell-cycle regulator and have shown that its expression level was closely related to cell-proliferation capacity. Herein, we found that Tudor-SN was highly expressed in neonatal mouse myocardia, but it was lowly expressed in that of adults. Using Data Base of Transcription Start Sites (DBTSS), we revealed that

Indexed as

Protein BiosynthesisAnimalsAnimals, NewbornCell LineCell ProliferationCells, CulturedEndonucleasesGene Expression RegulationHEK293 CellsHumansMechanistic Target of Rapamycin Complex 1MiceMice, Inbred C57BLMyocardiumMyocytes, CardiacRatsEndonucleasesMechanistic Target of Rapamycin Complex 1RNA, MessengerSnd1 protein, mousecardiomyocytic proliferationcell cycle arrestmTORC1TOP mRNAtranslational efficiencyTudor-SN

Identifiers

PMID33054526
PMCPMC8081040
OpenAlexW3092832268

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.