Evidence map›Paper›PMID 33054398›Full record

ArticleArteriosclerosis, thrombosis, and vascular biology2020

Naive CD8

Lindsey E Padgett, Huy Q Dinh, Runpei Wu, Dalia E Gaddis, Daniel J Araujo, Holger Winkels, Anh Nguyen, Coleen A McNamara, Catherine C Hedrick

Erratum issuedOpen access · bronzeAbstract read
In one paragraph

Article in Arteriosclerosis, thrombosis, and vascular biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 20 citations in OpenAlex.

  1. CD8Nature reviews. Cardiology · 2026
    Review
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. The role of T cells in age-related diseases.Nature reviews. Immunology · 2022
    Review
  14. Article
  15. Review
  16. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Lindsey E PadgettDivision of Inflammation Biology, La Jolla Institute for Immunology, CA (L.E.P., H.Q.D., R.W., D.E.G., D.J.A., H.W., C.C.H.).
Huy Q DinhDivision of Inflammation Biology, La Jolla Institute for Immunology, CA (L.E.P., H.Q.D., R.W., D.E.G., D.J.A., H.W., C.C.H.).
Runpei WuDivision of Inflammation Biology, La Jolla Institute for Immunology, CA (L.E.P., H.Q.D., R.W., D.E.G., D.J.A., H.W., C.C.H.).
Dalia E GaddisDivision of Inflammation Biology, La Jolla Institute for Immunology, CA (L.E.P., H.Q.D., R.W., D.E.G., D.J.A., H.W., C.C.H.).
Daniel J AraujoDivision of Inflammation Biology, La Jolla Institute for Immunology, CA (L.E.P., H.Q.D., R.W., D.E.G., D.J.A., H.W., C.C.H.).
Holger WinkelsDivision of Inflammation Biology, La Jolla Institute for Immunology, CA (L.E.P., H.Q.D., R.W., D.E.G., D.J.A., H.W., C.C.H.).
Anh NguyenCardiovascular Research Center and Division of Cardiovascular Medicine, University of Virginia, Charlottesville (A.N., C.A.M.).
Coleen A McNamaraCardiovascular Research Center and Division of Cardiovascular Medicine, University of Virginia, Charlottesville (A.N., C.A.M.).
Catherine C HedrickDivision of Inflammation Biology, La Jolla Institute for Immunology, CA (L.E.P., H.Q.D., R.W., D.E.G., D.J.A., H.W., C.C.H.).
La Jolla Institute for Immunology · USAnna Needs Neuroblastoma Answers · USUniversity of Virginia · US

Funding

ROLE OF LIPOXYGENASES IN ATHEROGENESIS IN DIABETES MELLITUSP01HL055798 · NHLBI · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI MCNAMARA, COLEEN A · 1995 to 2016
$28.4M
Project 4: APOB-specific CD4 and CD8 T cells exacerbate atherosclerosisP01HL136275 · NHLBI · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI Catherine C Hedrick · 2017 to 2026
$25.5M
Training in Immunological MechanismsT32AI125179 · NIAID · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI CROFT, MICHAEL · 2016 to 2025
$3.1M
Transcriptional Control of Monocyte DevelopmentR01HL134236 · NHLBI · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI HEDRICK, CATHERINE C · 2016 to 2019
$2.5M
Functions of Nonclassical Monocytes in the VasculatureR01CA202987 · NCI · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI HEDRICK, CATHERINE C · 2016 to 2020
$2.2M
Genetic Regulation of B Lymphocyte Aortic Homing and AtheroprotectionR01HL107490 · NHLBI · UNIVERSITY OF VIRGINIA · PI MCNAMARA, COLEEN A · 2011 to 2014
$1.5M
CyTOF Mass CytometerS10OD018499 · OD · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI CROTTY, SHANE P · 2014 to 2014
$802k
FACSAria II Cell SorterS10RR027366 · NCRR · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI CROFT, MICHAEL · 2011 to 2011
$514k
Exploring a Novel CD8 T Cell Subset in Cardiovascular Disease Progression and AtherosclerosisF32HL146069 · NHLBI · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI PADGETT, LINDSEY E · 2019 to 2019
$48k
NCI NIH HHS R01 CA202987NCRR NIH HHS S10 RR027366NHLBI NIH HHS F32 HL146069NHLBI NIH HHS P01 HL055798NHLBI NIH HHS P01 HL136275NHLBI NIH HHS R01 HL107490NHLBI NIH HHS R01 HL134236NIAID NIH HHS T32 AI125179NIH HHS S10 OD018499
6 · The paper itself

Abstract

objectiveCardiovascular disease (CVD) remains a significant global health concern with a high degree of mortality. While CD4

conclusionsCD8

Indexed as

Adoptive TransferAdultAgedAged, 80 and overAnimalsAortic DiseasesAtherosclerosisCardiovascular DiseasesCase-Control StudiesCD8-Positive T-LymphocytesCytokinesDisease Models, Animalfas ReceptorFemaleHeart Disease Risk FactorsHumansCytokinesFAS protein, humanFas protein, mousefas Receptoratherosclerosiscardiovascular diseasesmortalitymyocardial infarctionT lymphocytes

Identifiers

PMID33054398
PMCPMC8184121
OpenAlexW3092843083

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.