Evidence map›Paper›PMID 33053897›Full record

ArticleAntioxidants (Basel, Switzerland)2020

Substance-P Restores Cellular Activity of ADSC Impaired by Oxidative Stress.

Jeong Seop Park, Jiyuan Piao, Gabee Park, Hyun Sook Hong

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Substance P-Mediated Vascular Protection Ameliorates Bone Loss.Oxidative medicine and cellular longevity · 2023
    Article
  5. Article
  6. Metformin attenuates HExperimental and therapeutic medicine · 2021
    Article
  7. Article
  8. Cellular Oxidative Stress.Antioxidants (Basel, Switzerland) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Jeong Seop ParkDepartment of Biomedical Science and Technology, Graduate School, Kyung Hee University, Seoul 02447, Korea.
Jiyuan PiaoDepartment of Genetic Engineering, College of Life Science and Graduate School of Biotechnology, Kyung Hee University, Yong In 17104, Korea.
Gabee ParkDepartment of Genetic Engineering, College of Life Science and Graduate School of Biotechnology, Kyung Hee University, Yong In 17104, Korea.
Hyun Sook HongDepartment of Biomedical Science and Technology, Graduate School, Kyung Hee University, Seoul 02447, Korea.
Kyung Hee University · KR

Funding

Ministry of Education 2018R1D1A1B0704104813
6 · The paper itself

Abstract

Oxidative stress induces cellular damage, which accelerates aging and promotes the development of serious illnesses. Adipose-derived stem cells (ADSCs) are novel cellular therapeutic tools and have been applied for tissue regeneration. However, ADSCs from aged and diseased individuals may be affected in vivo by the accumulation of free radicals, which can impair their therapeutic efficacy. Substance-P (SP) is a neuropeptide that is known to rescue stem cells from senescence and inflammatory attack, and this study explored the restorative effect of SP on ADSCs under oxidative stress. ADSCs were transiently exposed to H

Indexed as

adipose-derived stem cellsoxidative stressparacrine factorsSubstance-P

Identifiers

PMID33053897
PMCPMC7601553
OpenAlexW3092972211

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.