Evidence map›Paper›PMID 33053881›Full record

ArticleInternational journal of molecular sciences2020

1-Cinnamoyltrichilinin from

Hoibin Jeong, SeonJu Park, Seo-Young Kim, Su-Hyeon Cho, Myeong Seon Jeong, Song-Rae Kim, Jong Bok Seo, Seung Hyun Kim, Kil-Nam Kim

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Hoibin JeongChuncheon Center, Korea Basic Science Institute (KBSI), Chuncheon 24341, Korea.ORCID 0000-0002-0784-5386
SeonJu ParkChuncheon Center, Korea Basic Science Institute (KBSI), Chuncheon 24341, Korea.
Seo-Young KimChuncheon Center, Korea Basic Science Institute (KBSI), Chuncheon 24341, Korea.
Su-Hyeon ChoChuncheon Center, Korea Basic Science Institute (KBSI), Chuncheon 24341, Korea.
Myeong Seon JeongChuncheon Center, Korea Basic Science Institute (KBSI), Chuncheon 24341, Korea.
Song-Rae KimChuncheon Center, Korea Basic Science Institute (KBSI), Chuncheon 24341, Korea.
Jong Bok SeoSeoul Center, Korea Basic Science Institute (KBSI), Seoul 02841, Korea.ORCID 0000-0003-2058-5045
Seung Hyun KimCollege of Pharmacy, Yonsei Institute of Pharmaceutical Science, Yonsei University, Incheon 21983, Korea.ORCID 0000-0003-2613-0674
Kil-Nam KimChuncheon Center, Korea Basic Science Institute (KBSI), Chuncheon 24341, Korea.
Korea Basic Science Institute · KRYonsei University · KR

Funding

Korea Basic Science Institute C030360Korea Basic Science Institute C08200
6 · The paper itself

Abstract

Acute myeloid leukemia (AML) is an aggressive type of human leukemia with a low survival rate, and its complete remission remains challenging. Although chemotherapy is the first-line treatment of AML, it exerts toxicity in noncancerous cells when used in high doses, thus necessitating the development of novel compounds with a high therapeutic window. This study aimed to investigate the anticancer effects of several compounds derived from the fruits of

Indexed as

ApoptosisCell SurvivalHL-60 CellsHumansLimoninsMAP Kinase Signaling SystemMelia azedarachMolecular Structurep38 Mitogen-Activated Protein KinasesPlant ExtractsLimoninsp38 Mitogen-Activated Protein KinasesPlant Extractstrichilinin D1-cinnamoyltrichilininacute myeloid leukemiaapoptosislimonoidMelia azedarachnatural compoundp38 pathway

Identifiers

PMID33053881
PMCPMC7589825
OpenAlexW3091859793

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.