Evidence map›Paper›PMID 33053851›Full record

ArticleVaccines2020

Rubella Seroprevalence Boost in the Pediatric and Adolescent Population of Florence (Italy) as a Preventive Strategy for Congenital Rubella Syndrome (CRS).

Beatrice Zanella, Sara Boccalini, Benedetta Bonito, Marco Del Riccio, Federico Manzi, Emilia Tiscione, Paolo Bonanni, Working Group Dhs, Working Group AOUMeyer, Working Group Ausltc and 1 more

Abstract read
In one paragraph

Article in Vaccines, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Beatrice ZanellaDepartment of Health Sciences, University of Florence, 50134 Florence, Italy.ORCID 0000-0001-6718-1932
Sara BoccaliniDepartment of Health Sciences, University of Florence, 50134 Florence, Italy.ORCID 0000-0002-9695-7549
Benedetta BonitoDepartment of Health Sciences, University of Florence, 50134 Florence, Italy.
Marco Del RiccioMedical Specialization School of Hygiene and Preventive Medicine, University of Florence, 50134 Florence, Italy.ORCID 0000-0002-2742-0297
Federico ManziMedical Specialization School of Hygiene and Preventive Medicine, University of Florence, 50134 Florence, Italy.
Emilia TiscioneDepartment of Health Sciences, University of Florence, 50134 Florence, Italy.
Paolo BonanniDepartment of Health Sciences, University of Florence, 50134 Florence, Italy.ORCID 0000-0003-2875-3744
Working Group DhsMedical Specialization School of Hygiene and Preventive Medicine, University of Florence, 50134 Florence, Italy.ORCID 0000-0002-1196-7060
Working Group AOUMeyerMeyer Children's Hospital, 50139 Florence, Italy.
Working Group AusltcAUSL Toscana Centro, 50122 Florence, Italy.
Angela BechiniDepartment of Health Sciences, University of Florence, 50134 Florence, Italy.ORCID 0000-0002-6013-8779

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDespite the availability of an effective vaccine since the 1970s, rubella disease and, importantly, congenital rubella syndrome (CRS) remain a public health concern. The aim of this study was to analyze the rubella seroprevalence in the children population of the province of Florence and compare the obtained results to a previous survey conducted in 2005-2006.

methodsA qualitative measurement of anti-rubella antibodies was performed on 165 sera using the enzyme-linked immunosorbent Assay (ELISA). The anamnestic and vaccination status was also collected.

resultsOur study highlighted a very high rubella seroprevalence (85-100%) in our enrolled population. In the vaccinated group (153/165), 98.7% of them were positive to rubella antibodies.

conclusionsOur study showed the highest seroprevalence rate reached in the province of Florence for rubella in the last 15 years, thanks to the several successful vaccination campaigns promoted in the Tuscany region. Our findings in pediatric and adolescent subjects are a key factor in preventing CRS in adult life, specifically in childbearing women. Thus, the set goal will be to keep the awareness about the vaccination for this preventable disease high.

Indexed as

adolescentCRSeliminationFlorenceItalyMMRV vaccinationpediatricrubellaseroprevalencevaccination coverage

Identifiers

PMID33053851
PMCPMC7712445

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.