Evidence map›Paper›PMID 33053829›Full record

ArticlePharmaceuticals (Basel, Switzerland)2020

Antibacterial Drug-Release Polydimethylsiloxane Coating for 3D-Printing Dental Polymer: Surface Alterations and Antimicrobial Effects.

Hang-Nga Mai, Dong Choon Hyun, Ju Hayng Park, Do-Yeon Kim, Sang Min Lee, Du-Hyeong Lee

Open access · goldAbstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 34 citations in OpenAlex.

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  12. Special Issue "Novel Antibacterial Agents".Pharmaceuticals (Basel, Switzerland) · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Hang-Nga MaiInstitute for Translational Research in Dentistry, Kyungpook National University, Daegu 41940, Korea.
Dong Choon HyunDepartment of Polymer Science and Engineering, Kyungpook National University, Daegu 41566, Korea.
Ju Hayng ParkDepartment of Polymer Science and Engineering, Kyungpook National University, Daegu 41566, Korea.
Do-Yeon KimDepartment of Pharmacology, School of Dentistry, Kyungpook National University, Daegu 41940, Korea.
Sang Min LeeDepartment of Pharmacology, School of Dentistry, Kyungpook National University, Daegu 41940, Korea.
Du-Hyeong LeeInstitute for Translational Research in Dentistry, Kyungpook National University, Daegu 41940, Korea.ORCID 0000-0003-2803-7457
Kyungpook National University · KR

Funding

National Research Foundation of Korea 2020R1A2C4002518
6 · The paper itself

Abstract

Polymers are the most commonly used material for three-dimensional (3D) printing in dentistry; however, the high porosity and water absorptiveness of the material adversely influence biofilm formation on the surface of the 3D-printed dental prostheses. This study evaluated the effects of a newly developed chlorhexidine (CHX)-loaded polydimethylsiloxane (PDMS)-based coating material on the surface microstructure, surface wettability and antibacterial activity of 3D-printing dental polymer. First, mesoporous silica nanoparticles (MSN) were used to encapsulate CHX, and the combination was added to PDMS to synthesize the antibacterial agent-releasing coating substance. Then, a thin coating film was formed on the 3D-printing polymer specimens using oxygen plasma and thermal treatment. The results show that using the coating substance significantly reduced the surface irregularity and increased the hydrophobicity of the specimens. Remarkably, the culture media containing coated specimens had a significantly lower number of bacterial colony formation units than the noncoated specimens, thereby indicating the effective antibacterial activity of the coating.

Indexed as

3D-printingantibacterial agentcoatingdental polymermesoporous silica nanoparticlespolydimethylsiloxane

Identifiers

PMID33053829
PMCPMC7600417
OpenAlexW3092600379

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.