Evidence map›Paper›PMID 33052944›Full record

ArticlePloS one2020

Perioperative and anesthetic risk factors of surgical site infection in patients undergoing pancreaticoduodenectomy: A retrospective cohort study.

Saori Yamamoto, Yusuke Nagamine, Tetsuya Miyashita, Shiono Ito, Yurika Iwasawa, Michihiko Kawai, Shinsaku Saito, Tomohisa Tamai, Takahisa Goto

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Saori YamamotoDepartment of Anesthesiology and Critical Care Medicine, Yokohama City University Hospital, Yokohama, Kanagawa, Japan.
Yusuke NagamineDepartment of Anesthesiology and Critical Care Medicine, Yokohama City University Hospital, Yokohama, Kanagawa, Japan.ORCID 0000-0002-0443-5007
Tetsuya MiyashitaDepartment of Anesthesiology and Critical Care Medicine, Yokohama City University Hospital, Yokohama, Kanagawa, Japan.
Shiono ItoDepartment of Anesthesiology and Critical Care Medicine, Yokohama City University Hospital, Yokohama, Kanagawa, Japan.
Yurika IwasawaDepartment of Anesthesiology and Critical Care Medicine, Yokohama City University Hospital, Yokohama, Kanagawa, Japan.
Michihiko KawaiDepartment of Anesthesiology and Critical Care Medicine, Yokohama City University Hospital, Yokohama, Kanagawa, Japan.
Shinsaku SaitoDepartment of Anesthesiology and Critical Care Medicine, Yokohama City University Hospital, Yokohama, Kanagawa, Japan.
Tomohisa TamaiDepartment of Anesthesiology and Critical Care Medicine, Yokohama City University Hospital, Yokohama, Kanagawa, Japan.
Takahisa GotoDepartment of Anesthesiology and Critical Care Medicine, Yokohama City University Hospital, Yokohama, Kanagawa, Japan.
Yokohama City University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSurgical site infection is a major perioperative issue. The morbidity of surgical site infection is high in major digestive surgery, such as pancreaticoduodenectomy. The comprehensive risk factors, including anesthetic factors, for surgical site infection in pancreaticoduodenectomy are unknown. The aim of this study was to investigate the perioperative and anesthetic risk factors of surgical site infection in pancreaticoduodenectomy.

methodsThis was a retrospective cohort study conducted in a single tertiary care center. A total of 326 consecutive patients who underwent pancreaticoduodenectomy between January 2009 and March 2018 were evaluated. Patients who underwent resection of other organs were excluded. The primary outcome was the incidence of surgical site infection, based on a Clavien-Dindo classification of grade 2 or higher. Multivariable logistic regression analysis was performed to investigate the association between surgical site infection and perioperative and anesthetic factors.

resultsOf the 326 patients, 116 (35.6%) were women. The median age was 70 years (interquartile range; 64-75). The median duration of surgery was 10.9 hours (interquartile range; 9.5-12.4). Surgical site infection occurred in 60 patients (18.4%). The multivariable analysis revealed that the use of desflurane as a maintenance anesthetic was associated with a significantly lower risk of surgical site infection than sevoflurane (odds ratio, 0.503; 95% confidence interval [CI], 0.260-0.973). In contrast, the duration of surgery (odds ratio, 1.162; 95% CI, 1.017-1.328), cerebrovascular disease (odds ratio, 3.544; 95% CI, 1.326-9.469), and ischemic heart disease (odds ratio, 10.839; 95% CI, 1.887-62.249) were identified as significant risk factors of surgical site infection.

conclusionsDesflurane may be better than sevoflurane in preventing surgical site infection in pancreaticoduodenectomy. Cerebrovascular disease and ischemic heart disease are potential newly-identified risk factors of surgical site infection in pancreaticoduodenectomy.

Indexed as

AgedAnestheticsComorbidityDesfluraneFemaleHumansIncidenceJapanMaleOperative TimePancreaticoduodenectomyPerioperative PeriodRetrospective StudiesRisk FactorsSevofluraneSurgical Wound InfectionAnestheticsDesfluraneSevoflurane

Identifiers

PMID33052944
PMCPMC7556444
OpenAlexW3093187729

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.