Evidence map›Paper›PMID 33052928›Full record

ArticlePloS one2020

Optical characteristics after Descemet membrane endothelial keratoplasty: 1-year results.

Takahiko Hayashi, Akira Kobayashi, Hidenori Takahashi, Itaru Oyakawa, Naoko Kato, Takefumi Yamaguchi

Abstract read
In one paragraph

Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
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  4. Intracellular dark endothelial spots detected using specular microscopy are associated with graft failure after Descemet's membrane endothelial keratoplasty.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025
    Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Risk factors for intraocular pressure elevation following Descemet membrane endothelial keratoplasty in Asian patients.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023
    Article
  10. Optimizing intraocular lens power calculation using adjusted conventional keratometry for cataract surgery combined with Descemet membrane endothelial keratoplasty.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2022
    Article
  11. Descemet membrane endothelial keratoplasty in eyes withAmerican journal of ophthalmology case reports · 2022
    Article
  12. Article
  13. Article
  14. Toric IOL in Combined DMEK and Cataract Surgery.Clinical ophthalmology (Auckland, N.Z.) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Takahiko HayashiDepartment of Ophthalmology, Yokohama Minami Kyosai Hospital, Yokohama, Kanagawa, Japan.ORCID 0000-0001-8704-680X
Akira KobayashiDepartment of Ophthalmology, Graduate School of Medical Science, Kanazawa University, Kanazawa, Japan.
Hidenori TakahashiDepartment of Ophthalmology, Jichi Medical University, Shimotsuke, Tochigi, Japan.ORCID 0000-0001-5331-4730
Itaru OyakawaDepartment of Ophthalmology, Heart Life Hospital, Nakagami-gun, Okinawa, Japan.
Naoko KatoDepartment of Ophthalmology, Yokohama Minami Kyosai Hospital, Yokohama, Kanagawa, Japan.ORCID 0000-0002-6670-2043
Takefumi YamaguchiDepartment of Ophthalmology, Tokyo Dental College, Ichikawa General Hospital, Chiba, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the corneal characteristics after Descemet membrane endothelial keratoplasty (DMEK) compared with normal corneas.

methodsPatients who underwent DMEK at Yokohama Minami Kyosai Hospital were included and prospectively evaluated pre-operatively and at postoperative months 1, 3, 6, and 12, and compared to healthy controls. Corneal characteristics evaluated included corneal curvature (keratometric value [KV]; D), central corneal thickness (CCT), peripheral corneal thickness (PCT), and corneal higher-order aberrations [HOAs] at 6.0 mm diameter, calculated by anterior segment optical coherence tomography and logarithm of the minimal angle of resolution [logMAR].

resultsA total of 30 eyes of 30 patients (6 men, 24 women, mean age 73.4 ± 7.4 years) were included and compared with 31 age-matched healthy control eyes (13 men, 18 women; mean age 73.0 ± 6.7 years). LogMAR after DMEK improved from 0.87 ± 0.07 preoperatively to 0.04 ± 0.07 at 12 months postoperatively (p<0.001). Although anterior KVs of DMEK eyes were similar to those of control eyes, posterior KVs were significantly larger (-6.4 ± 0.3 D vs. -6.3 ± 0.2 D; p = 0.02). Total HOAs after DMEK improved from 1.94 ± 1.05 μm preoperatively to 1.05 ± 0.16 μm at 12 months postoperatively (p<0.001), which was significantly higher than that in control eyes (0.63 ± 0.06) (p<0.001). Despite the similar CCTs in the two groups, the PCT was significantly larger in DMEK eyes (704 ± 41 μm vs 669 ± 38 μm, p = 0.002) at 12 months.

conclusionDespite achieving good visual function and excellent corneal clarity, eyes that underwent DMEK showed a steeper posterior KV and higher corneal HOAs than normal eyes even at 12 months after surgery.

Indexed as

AgedAged, 80 and overCase-Control StudiesCorneaDescemet Stripping Endothelial KeratoplastyFemaleHumansMaleProspective StudiesTomography, Optical CoherenceVisual Acuity

Identifiers

PMID33052928
PMCPMC7556451

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.