Evidence map›Paper›PMID 33052829›Full record

ReviewTurkish journal of urology2020

Is Thulium laser enucleation of prostate an alternative to Holmium and TURP surgeries - A systematic review?

Mudassir M Wani, Seshadri Sriprasad, Tahir Bhat, Sanjeev Madaan

Registry-linked trialOpen access · greenAbstract readReview
In one paragraph

Review in Turkish journal of urology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06565741 (Prospective and Randomized Analysis of Endoscopic Prostate Enucleation Using Moses 2.0 Technology Versus the New Thulium Fiber Laser in Medium and Large Prostates.), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06565741 narecruitingnot on this mapstarted 2024, after this paper: background citation

Prospective and Randomized Analysis of Endoscopic Prostate Enucleation Using Moses 2.0 Technology Versus the New Thulium Fiber Laser in Medium and Large Prostates.

TypeinterventionalSponsorFundacio PuigvertRan2024 to 2028Enrolled120ConditionsProstatic Hyperplasia, Surgery, Endoscopic Anatomical Enucleation of the Prostate (EEAP)ArmsMoLEP, ThuFLEP
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Mudassir M WaniCanterburry University, Working as Specialty Registrar at Medway Maritime Hospital, Kent, UK.ORCID http://orcid.org/0000-0001-8940-2310
Seshadri SriprasadConsultant Urological Surgeon & Lead Clinician, Darent Valley Hospital, Dartford Professor, Canterbury Christ Church University, UK.ORCID http://orcid.org/0000-0002-7654-0092
Tahir BhatConsultant Urological Surgeon, Medway Maritime Hospital, Kent UK.ORCID http://orcid.org/0000-0002-4501-5340
Sanjeev MadaanConsultant Urological Surgeon & Lead Cancer Clinician, Darent Valley Hospital, Dartford Visiting Professor, Canterbury Christ Church University, UK.ORCID http://orcid.org/0000-0003-4220-5613
Darent Valley Hospital · GBMedway Maritime Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To assess efficacy and safety of Thulium laser enucleation of prostate (ThuLEP) for benign prostatic hyperplasia. It is a systemic review based on a comprehensive search of PubMed, Cochrane, and Google scholar databases from inception to 31 March 2020. All studies in English evaluating ThuLEP as well as those comparing it with Transurethral resection of prostate (TURP) and Holmium Laser enucleation of prostate (HoLEP) were enrolled. The primary outcome was to evaluate operative, postoperative, and functional outcomes (IPSS, QoL, Qmax, PVR) in patients undergoing ThuLEP. Secondary outcome was to compare operative, postoperative, and functional outcomes with TURP and HoLEP in comparative studies. Fourteen studies with a total of 2,562 patients were included in this review. 2,034 underwent ThuLEP, 349 underwent TURP, and remaining 139 had HoLEP. We found that ThuLEP is safe as well as efficacious in all age groups as well as across all prostate sizes and with all four functional outcomes (IPSS, QoL, Qmax, PVR) revealing marked improvement at 3, 6, 12, and 24 months. Compared to TURP and HoLEP, Thulep is non-inferior in terms of operative and functional outcomes and, in fact, is associated with lesser catheterization duration as well as shorter hospital stay. Further, Thulium fiber laser (TFL) has advantages of being light weight, having high frequency, less fiber degradation, and less energy consumption, making it cost effective for operational and maintenance purpose. ThuLEP is a safe, efficacious, and cost-effective procedure for BPE.

Identifiers

PMID33052829
PMCPMC7608540
OpenAlexW3092874235

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.