ReviewAnnals of the American Thoracic Society2021
Mask Use with Spacers/Valved Holding Chambers and Metered Dose Inhalers among Children with Asthma.
Review in Annals of the American Thoracic Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 22 citations in OpenAlex.
- Article
- Pediatric Inhaled Medication: A Cross-Sectional Analysis on Usage Trends and Parental Perceptions in Romania.Children (Basel, Switzerland) · 2025Article
- Time to face mask/spacer acceptance in dogs and cats.The Canadian veterinary journal = La revue veterinaire canadienne · 2025Article
- Level of agreement between two asthma control questionnaires in children and adolescents.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2025Article
- Real-World Use of Inhaled COPD Medications: the Good, the Bad, the Ugly.Chronic obstructive pulmonary diseases (Miami, Fla.) · 2024Article
- Article
- From the infant to the geriatric patient-Strategies for inhalation therapy in asthma and chronic obstructive pulmonary disease.The clinical respiratory journal · 2023Review
- Utility of a Mask with a Spacer to Deliver the Contents of a Metered Dose Inhaler.Annals of the American Thoracic Society · 2021Article
- Reply: Utility of a Mask with a Spacer to Deliver the Contents of a Metered Dose Inhaler.Annals of the American Thoracic Society · 2021Article
- Strategies for Improving Inhalation Technique in Children: A Narrative Review.Patient preference and adherence · 2021Review
- Impact of Improper Inhaler Technique on Pediatric Asthma Control in Vietnam: A Cross-Sectional Study.Sage open pediatricsArticle
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
Inhaler misuse is highly prevalent and associated with high morbidity and costs. For metered dose inhalers, proper use can be supported with devices such as spacers/valved holding chambers (VHCs) and masks to effectively deliver inhaled medication to the lungs. However, guidelines are vague about which children with asthma should use spacers/VHCs with masks to deliver medication from metered dose inhalers as well as when they should transition to spacers/VHCs with mouthpieces. In this paper, we provide a focused review of the evidence for mask use, highlighting unclear and conflicting information in guidelines and studies. We synthesize the differences in recommendations and practice. Based on these findings, we call for future research to determine the appropriate age and necessary skills for transitioning children from using metered dose inhalers with spacers/VHCs and masks to using spacers/VHCs and mouthpieces. Guidelines about mask use should be standardized to help ensure optimal medical delivery for patients, provide consistent inhaler prescriptions and education across settings, and support team-based care to help lower pediatric asthma morbidity and costs.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.