SynthesisWorld journal of urology2021
Tea and coffee consumption and pathophysiology related to kidney stone formation: a systematic review.
Synthesis in World journal of urology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 2 syntheses or guidelines pooled it, 61 citations in OpenAlex.
- Association between tea consumption and risk of kidney stones: results from dose-response meta-analysis of prospective studies and Mendelian randomization analysis.International urology and nephrology · 2024Pooled it
- Univariable and multivariable mendelian randomization study revealed the modifiable risk factors of urolithiasis.PloS one · 2023Pooled it
- Patient awareness and perceptions of a kidney stone multidisciplinary team (MDT): a questionnaire survey.World journal of urology · 2026Article
- Sodium-glucose cotransporter 2 inhibitorsTranslational andrology and urology · 2026Review
- Machine Learning Approaches to Predict 24-Hour Urine Collection Results Based on Self-Reported Beverage Intake.Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation · 2026Article
- Time-Restricted Feeding With High-Fat Diet Slows Weight Gain and Reduces Renal Calcium Oxalate Crystal Formation Without Reducing Energy Intake.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026Article
- Assessing Risk of Nephrolithiasis in Urology Residents: Are We Practicing What We Preach?Cureus · 2026Article
- Hydration status, thirst discomfort, and ocular surface health among older adults in Türkiye: a cross-sectional study.BMC geriatrics · 2026Article
- Climatic effects on urinary hippuric acid concentrations: a 3-year occupational health study in a manufacturing workforce.Journal of occupational health · 2026Article
- Social Media's Impact on Public Awareness of the Effects of Dietary Habits and Fluid Consumption on Kidney Stone Formation: A Cross-Sectional Study.Healthcare (Basel, Switzerland) · 2025Article
- Higher Life's Essential 8 score is associated with lower risk of kidney stones in Chinese adults: a cross-sectional study.BMC public health · 2025Article
- Dietary Influence on Urolithiasis Risk Mediated by Plasma Metabolites: A Mendelian Randomization and Experimental Study Linking Genes, Metabolites, and Clinical Outcomes.Food science & nutrition · 2025Article
- Causal Relationships Between Dietary Habits, Gut Microbiota, Metabolites, Serum Proteins and Laboratory Biomarkers in Kidney Stone Formation: A Mendelian Randomisation Study.Journal of cellular and molecular medicine · 2025Article
- Both absolute and relative sugar-sweetened beverage intake are associated with kidney stones in U.S. middle-aged and young adults.World journal of urology · 2025Article
- Neutrophils as mediators of the association between lipid accumulation product and kidney stones, but not for recurrent kidney stones in US adults.Urolithiasis · 2025Article
- Review
- The association between urinary lead concentration and the likelihood of kidney stones in US adults: a population-based study.Scientific reports · 2025Article
- The S-shaped association between dietary caffeine intake and severe headache or migraine: a cross-sectional study based on NHANES.Frontiers in neurology · 2025Article
- Impact of diet on renal stone formation.Journal of family medicine and primary care · 2024Review
- Effects of multiple fluid intake on Urolithiasis by mendelian randomization study.Scientific reports · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo explore the mechanisms behind the potential protective effect of coffee and tea consumption, regarding urinary stone formation, previously demonstrated in large epidemiological studies.
methodsA systematic review was performed using the Medline, Cochrane library (CENTRAL) and Scopus databases, in concordance with the PRISMA statement. English, French and Spanish language studies, regarding the consumption of caffeinated and decaffeinated coffee and tea, and the relationship to urinary stone formation were reviewed. Meta-analyses, systematic reviews, case reports and letters, unpublished studies, posters and comments abstracts were excluded.
resultsAs per the inclusion criteria, 13 studies were included in the final review. The major findings show that caffeine increases urinary excretion of calcium, sodium and magnesium, in addition to a diuretic action with consumption > 300-360 mg (approximately four cups of coffee). Together with other components of coffee, this beverage might have potential protective effects against the formation of urinary stones. Tea exerts many protective effects against stone formation, through the accompanying water intake, the action of caffeine and the effects of components with antioxidant properties.
conclusionCaffeine has a hypercalciuric effect, balanced partially by a diuretic effect which appears after consumption of large quantities of caffeine. The current available literature supports in general, a potentially protective role for tea against stone formation, mainly for green tea. Additional standardization in this field of research, through specification of tea and coffee types studied, and their respective compositions, is needed for further clarification of the relation between coffee, tea and urinary stones.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.