Evidence map›Paper›PMID 33052294›Full record

ArticleCureus2020

Thyroid Storm Presenting as Acute Liver Failure in a Patient with Graves' Disease.

Muhammad Hashim Hayat, Zorays Moazzam, Ioannis A Ziogas, Amman Yousaf, Maham Hayat

Abstract readCase Reports
In one paragraph

Article in Cureus, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Thyrotoxicosis in MCT8 deficiency.The Journal of clinical endocrinology and metabolism · 2026
    Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Liver Dysfunction in Hyperthyroidism.Hepatic medicine : evidence and research · 2024
    Article
  9. Article
  10. Article
  11. Fatal Case of Possible Thyroid Crisis Induced by SARS-CoV-2 Infection: A Case Report.Journal of the ASEAN Federation of Endocrine Societies · 2022
    Article
  12. Effect ofFrontiers in endocrinology · 2022
    Article
  13. [Diagnosis and treatment of new-onset or uncontrolled hyperthyroidism-induced liver injury].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2021
    Review
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Muhammad Hashim HayatInternal Medicine: Gastroenterology, Vanderbilt University Medical Center, Nashville, USA.
Zorays MoazzamInternal Medicine, Aga Khan University Hospital, Karachi, PAK.
Ioannis A ZiogasDepartment of Surgery, Division of Hepatobiliary Surgery and Liver Transplantation, Vanderbilt University Medical Center, Nashville, USA.
Amman YousafRadiology, Hamad General Hospital, Doha, QAT.
Maham HayatDepartment of Digestive Diseases and Nutrition, University of Oklahoma Health Sciences Center, Oklahoma, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although mild elevations in liver enzymes are relatively common in thyrotoxicosis, acute liver failure (ALF) is an infrequent occurrence. Despite the emergence of liver transplantation as a viable treatment for ALF, survival rates continue to remain unsatisfactory, coupled with higher rates of postoperative complications and re-transplantation in this group. We present the disease course, management, and outcome of a patient with Graves' disease who presented with ALF secondary to thyroid storm. Thyrotoxicosis should always be included in the differential diagnosis of ALF, as timely diagnosis and management are crucial in achieving survival.

Indexed as

acute liver failurehyperthyroidismthyrotoxicosis

Identifiers

PMID33052294
PMCPMC7546597

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.