Evidence map›Paper›PMID 33052279›Full record

ArticleCureus2020

Acute Severe Hyponatremia Induced by a Duloxetine Overdose in an Elderly Woman.

Wesley D Oliver, Ryan D'Angelo, Jeffrey Gonzales, Tracey Wilson, Leah S Millstein

Abstract readCase Reports
In one paragraph

Article in Cureus, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Wesley D OliverEmergency Medicine, University of Maryland Medical Center, Baltimore, USA.
Ryan D'AngeloCardiology, Thomas Jefferson University Hospital, Philadelphia, USA.
Jeffrey GonzalesInternal Medicine: Critical Care, None, Baltimore, USA.
Tracey WilsonMedical Intensive Care Unit, University of Maryland Medical Center, Baltimore, USA.
Leah S MillsteinInternal Medicine - Pediatrics, University of Maryland School of Medicine, Baltimore, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report a case of acute severe hyponatremia within 24 hours after a duloxetine overdose. An 82-year-old woman presented to the ED after ingesting duloxetine and diltiazem. She became hemodynamically unstable due to the diltiazem overdose and was appropriately resuscitated. During hospitalization she experienced hyponatremia consistent with syndrome of inappropriate antidiuretic hormone (SIADH). Based on the observations we concluded there was a probable relationship between the hyponatremia and the duloxetine overdose. Clinicians should monitor patients' electrolytes for acute disturbances after an overdose of duloxetine.

Indexed as

duloxetinehyponatremiaoverdosesyndrome of inappropriate antidiuretic hormone secretion

Identifiers

PMID33052279
PMCPMC7546372

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.