Evidence map›Paper›PMID 33052236›Full record

ArticleTheranostics2020

Hemoglobin-mediated biomimetic synthesis of paramagnetic O

Xiudong Shi, Weitao Yang, Qiong Ma, Yang Lu, Yan Xu, Kexin Bian, Fengjun Liu, Chunzi Shi, Han Wang, Yuxin Shi and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Theranostics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 62 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. Review
  8. Innovative strategies for photodynamic therapy against hypoxic tumor.Asian journal of pharmaceutical sciences · 2023
    Review
  9. Article
  10. Review
  11. Article
  12. Review
  13. Review
  14. Review
  15. Review
  16. Article
  17. Review
  18. Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Xiudong ShiDepartment of Radiology, Shanghai Public Health Clinical Center, Fudan University, Shanghai 201508, China.
Weitao YangThe Institute for Translational Nanomedicine, Shanghai East Hospital; The Institute for Biomedical Engineering & Nano Science, Tongji University School of Medicine, Shanghai 200092, China.
Qiong MaDepartment of Radiology, Shanghai Public Health Clinical Center, Fudan University, Shanghai 201508, China.
Yang LuDepartment of Radiology, Shanghai Public Health Clinical Center, Fudan University, Shanghai 201508, China.
Yan XuThe Institute for Translational Nanomedicine, Shanghai East Hospital; The Institute for Biomedical Engineering & Nano Science, Tongji University School of Medicine, Shanghai 200092, China.
Kexin BianThe Institute for Translational Nanomedicine, Shanghai East Hospital; The Institute for Biomedical Engineering & Nano Science, Tongji University School of Medicine, Shanghai 200092, China.
Fengjun LiuDepartment of Radiology, Shanghai Public Health Clinical Center, Fudan University, Shanghai 201508, China.
Chunzi ShiDepartment of Radiology, Shanghai Public Health Clinical Center, Fudan University, Shanghai 201508, China.
Han WangDepartment of Radiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China.
Yuxin ShiDepartment of Radiology, Shanghai Public Health Clinical Center, Fudan University, Shanghai 201508, China.
Bingbo ZhangThe Institute for Translational Nanomedicine, Shanghai East Hospital; The Institute for Biomedical Engineering & Nano Science, Tongji University School of Medicine, Shanghai 200092, China.
Shanghai Public Health Clinical Center · CNShanghai East Hospital · CNShanghai First People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The hypoxic microenvironment in solid tumors severely limits the efficacy of photodynamic therapy (PDT). Therefore, the development of nanocarriers co-loaded with photosensitizers and oxygen, together with imaging guidance ability, is of great significance in cancer therapy. However, previously reported synthetic methods for these multi-functional probes are complicated, and the raw materials used are toxic.

Indexed as

AnimalsAntineoplastic AgentsBiomimetic MaterialsCell Line, TumorChlorophyllidesDiffusion Magnetic Resonance ImagingDisease Models, AnimalFemaleGadoliniumGreen Chemistry TechnologyHemoglobinsHumansInjections, IntravenousMetal NanoparticlesMiceMolecular ProbesAntineoplastic AgentsChlorophyllidesGadoliniumHemoglobinsMolecular ProbesOxygenphytochlorinPorphyrinsbiomimetic synthesisendogenous proteinMR imagingphotodynamic therapytumor hypoxia

Identifiers

PMID33052236
PMCPMC7545996
OpenAlexW3089239131

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.