Evidence map›Paper›PMID 33052235›Full record

Observational studyTheranostics2020

Human oral microbiome dysbiosis as a novel non-invasive biomarker in detection of colorectal cancer.

Sheng Zhang, Cheng Kong, Yongzhi Yang, Sanjun Cai, Xinxiang Li, Guoxiang Cai, Yanlei Ma

Open access · goldAbstract readObservational StudyValidation Study
In one paragraph

Observational study in Theranostics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
73citing papers in PubMed, 2 pooled it
9.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

73 citing papers in PubMed, 2 syntheses or guidelines pooled it, 104 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Gut microbes · 2026
    Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Lower respiratory tract microbiota characteristics in patients withFrontiers in cellular and infection microbiology · 2026
    Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Review
  14. Review
  15. Review
  16. Article
  17. Oral microbes and gastrointestinal cancers: new strategies and insights.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2025
    Review
  18. Review
  19. New advances in oral microbiology and tumor research.World journal of clinical oncology · 2025
    Review
  20. Review

13 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Sheng ZhangDepartment of Colorectal Surgery, Fudan University Shanghai Cancer Center, Shanghai, China.
Cheng KongDepartment of GI Surgery, Shanghai Tenth People's Hospital Affiliated to Tongji University, Shanghai, China.
Yongzhi YangDepartment of Colorectal Surgery, Fudan University Shanghai Cancer Center, Shanghai, China.
Sanjun CaiDepartment of Colorectal Surgery, Fudan University Shanghai Cancer Center, Shanghai, China.
Xinxiang LiDepartment of Colorectal Surgery, Fudan University Shanghai Cancer Center, Shanghai, China.
Guoxiang CaiDepartment of Colorectal Surgery, Fudan University Shanghai Cancer Center, Shanghai, China.
Yanlei MaDepartment of Colorectal Surgery, Fudan University Shanghai Cancer Center, Shanghai, China.
Fudan University Shanghai Cancer Center · CNShanghai Medical College of Fudan University · CNTongji University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdultAgedBiomarkers, TumorCase-Control StudiesColorectal NeoplasmsDNA, BacterialDysbiosisFemaleGastrointestinal MicrobiomeHumansMaleMiddle AgedMouth MucosaProspective StudiesRisk AssessmentRNA, Ribosomal, 16SBiomarkers, TumorDNA, BacterialRNA, Ribosomal, 16S16S rRNAcolorectal adenomascolorectal cancersoral microbiome

Identifiers

PMID33052235
PMCPMC7545992
OpenAlexW3089313366

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.