Evidence map›Paper›PMID 33052181›Full record

ArticleJournal of clinical and experimental hepatology

Restructuring Living-Donor Liver Transplantation at a High-Volume Center During the COVID-19 Pandemic.

Arvinder S Soin, Narendra S Choudhary, Sanjay K Yadav, Sanjiv Saigal, Neeraj Saraf, Amit Rastogi, Prashant Bhangui, Thiagarajan Srinivasan, Neelam Mohan, Sujeet K Saha and 7 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of clinical and experimental hepatology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.8field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. Article
  3. Pediatric transplantation during the COVID-19 pandemic.World journal of transplantation · 2022
    Review
  4. Coronavirus Precautions: Experience of High Volume Liver Transplant Institute.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2022
    Article
  5. Review
  6. Living Donor Liver Transplantation During the COVID-19 Pandemic: an Evolving Challenge.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2021
    Article
  7. Article
  8. Article
  9. Liver Transplantation Services During the Time of COVID-19.Journal of clinical and translational hepatology · 2021
    Review
  10. Review
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 1 institution in 1 country.

Arvinder S SoinInstitute of Liver Transplantation and Regenerative Medicine, Medanta the Medicity, Gurgaon, Delhi (NCR), India.
Narendra S ChoudharyInstitute of Liver Transplantation and Regenerative Medicine, Medanta the Medicity, Gurgaon, Delhi (NCR), India.
Sanjay K YadavInstitute of Liver Transplantation and Regenerative Medicine, Medanta the Medicity, Gurgaon, Delhi (NCR), India.
Sanjiv SaigalInstitute of Liver Transplantation and Regenerative Medicine, Medanta the Medicity, Gurgaon, Delhi (NCR), India.
Neeraj SarafInstitute of Liver Transplantation and Regenerative Medicine, Medanta the Medicity, Gurgaon, Delhi (NCR), India.
Amit RastogiInstitute of Liver Transplantation and Regenerative Medicine, Medanta the Medicity, Gurgaon, Delhi (NCR), India.
Prashant BhanguiInstitute of Liver Transplantation and Regenerative Medicine, Medanta the Medicity, Gurgaon, Delhi (NCR), India.
Thiagarajan SrinivasanInstitute of Liver Transplantation and Regenerative Medicine, Medanta the Medicity, Gurgaon, Delhi (NCR), India.
Neelam MohanPaediatric Gastroenterology and Hepatology, Medanta the Medicity, Gurgaon, Delhi (NCR), India.
Sujeet K SahaInstitute of Liver Transplantation and Regenerative Medicine, Medanta the Medicity, Gurgaon, Delhi (NCR), India.
Ankur GuptaInstitute of Liver Transplantation and Regenerative Medicine, Medanta the Medicity, Gurgaon, Delhi (NCR), India.
Rohan J ChaudharyInstitute of Liver Transplantation and Regenerative Medicine, Medanta the Medicity, Gurgaon, Delhi (NCR), India.
Kamal YadavInstitute of Liver Transplantation and Regenerative Medicine, Medanta the Medicity, Gurgaon, Delhi (NCR), India.
Swapnil DhampalwarInstitute of Liver Transplantation and Regenerative Medicine, Medanta the Medicity, Gurgaon, Delhi (NCR), India.
Deepak GovilCritical Care, Medanta the Medicity, Gurgaon, Delhi (NCR), India.
Nikunj GuptaLiver Transplant Anesthesia, Medanta the Medicity, Gurgaon, Delhi (NCR), India.
Vijay VohraLiver Transplant Anesthesia, Medanta the Medicity, Gurgaon, Delhi (NCR), India.
Medanta The Medicity · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCoronavirus disease 2019 (COVID-19) pandemic has led to deferral of elective transplants and proactive pretransplant testing of the donor/recipient. The impact of these on living-donor liver transplantation (LDLT) activity and outcome is not known. We performed LDLT only for sick patients or patients with advanced hepatocellular carcinoma in this period, with special COVID protocols.

methodsPatients undergoing LDLT counseling, evaluation, and transplant in the period March to June 2020 (group A) under COVID-19 restrictions and special protocols were included. LDLT activity and outcomes among these patients were compared with those in the same period in 2019 (group B).

resultsIn the period March 15-June 10, we performed 39 and 23 (59%) LDLTs in 2019 and 2020, respectively. The adult patients with cirrhosis in group A (n = 20) had a significantly higher MELD score, 19.8 ± 7.0 versus 16.1 ± 5.6 in group B (n = 36), p = 0.034. Early recipient mortality was similar in 2019 (2/39) and 2020 (2/23). One of 23 post-transplant recipients, 3/71 recipients and donors during evaluation, and 8/125 healthcare workers (HCWs) developed COVID-19, all of whom recovered uneventfully.

conclusionLDLT activity substantially reduced during the COVID era. The incidence and outcome of COVID-19 among the waiting or transplanted patients and HCWs were similar to those of the general population. The outcome after LDLT in the COVID era was similar to that in non-COVID times. These data suggest that LDLT may be extended to more stable patients with strict protocols.

Indexed as

CirrhosisCOVIDCOVID-19, Coronavirus disease 2019CTP scoreDisease severityHCC, hepatocellular carcinomaHCWs, healthcare workersHepatocellular carcinomaIndiaLDLT, living-donor liver transplantationLockdownLTSI, Liver Transplantation Society of IndiaMDT, multidisciplinary teamMELD scorePandemicPPE, personal protective equipment

Identifiers

PMID33052181
PMCPMC7543734
OpenAlexW3091833868

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.