SynthesisClinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
Risk Factors for Early Pancreatic Allograft Thrombosis Following Simultaneous Pancreas-Kidney Transplantation: A Systematic Review.
Synthesis in Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 29 citations in OpenAlex.
- Heparin Thromboprophylaxis in Simultaneous Pancreas-Kidney Transplantation: A Systematic Review and Meta-Analysis of Observational Studies.Transplant international : official journal of the European Society for Organ Transplantation · 2023Pooled it
- Interventions for preventing thrombosis in solid organ transplant recipients.The Cochrane database of systematic reviews · 2021Pooled it
- Does graft implantation sequence affect post-transplant outcome in simultaneous pancreas-kidney transplantation? An analysis of a nationwide registry in Japan.Surgery today · 2026Article
- Day-Zero Serum FTIR Spectroscopy Identifies a Biochemical Signature Associated with Functional Pancreas Graft Dysfunction After Simultaneous Pancreas-Kidney Transplantation.Life (Basel, Switzerland) · 2026Article
- Phase-specific intraoperative glycemic control in simultaneous pancreas-kidney transplantation.World journal of transplantation · 2026Review
- The rebirth of pancreas transplantation: an innovative, fully robotic, reproducible surgical technique.BMC surgery · 2026Review
- Pre-Transplant Serum FTIRS Signatures as Predictive Biomarkers of Early Transient Pancreatic Graft Dysfunction in Simultaneous Pancreas-Kidney Transplantation.Life (Basel, Switzerland) · 2026Article
- Endocrine-related neurological function recovery in pancreatic transplantation.World journal of transplantation · 2025Article
- Article
- Use of resuscitative endovascular balloon occlusion of the aorta in ruptured pseudoaneurysm after simultaneous pancreas-kidney transplantation.Journal of vascular surgery cases and innovative techniques · 2025Article
- Outcome-Orientated Organ Allocation-A Composite Risk Model for Pancreas Graft Evaluation and Acceptance.Journal of clinical medicine · 2024Article
- Local Postoperative Graft Inflammation in Pancreas Transplant Patients With Early Graft Thrombosis.Transplantation direct · 2024Article
- Surgical complications after pancreatic transplantation: A computed tomography imaging pictorial review.World journal of gastroenterology · 2023Review
- Pancreatic Allograft Thrombosis: Implementation of the CPAT-Grading System in a Retrospective Series of Simultaneous Pancreas-Kidney Transplantation.Transplant international : official journal of the European Society for Organ Transplantation · 2023Article
- Thromboinflammatory response is increased in pancreas transplant alone versus simultaneous pancreas-kidney transplantation and early pancreas graft thrombosis is associated with complement activation.Frontiers in immunology · 2023Observational
- Different timing and risk factors of cause-specific pancreas graft loss after simultaneous pancreas kidney transplantation.Scientific reports · 2022Article
- Simultaneous pancreas-kidney transplantation: Early complications and long-term outcomes - a single-center experience.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2022Article
- Evaluation of the Efficacy and Effects of Common Hepatic Artery Reconstruction in Pancreas Transplantation: A Randomized Controlled Trial.Journal of clinical medicine · 2022Article
- Current Trends in Organ Preservation Solutions for Pancreas Transplantation: A Single-Center Retrospective Study.Transplant international : official journal of the European Society for Organ Transplantation · 2022Article
- Impact of Early Pancreatic Graft Loss on Outcome after Simultaneous Pancreas-Kidney Transplantation (SPKT)-A Landmark Analysis.Journal of clinical medicine · 2021Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Simultaneous pancreas-kidney (SPK) transplantation remains the most effective treatment for providing consistent and long-term euglycemia in patients having type 1 diabetes with renal failure. Thrombosis of the pancreatic vasculature continues to contribute significantly to early graft failure and loss. We compared the rate of thrombosis to graft loss and systematically reviewed risk factors impacting early thrombosis of the pancreas allograft following SPK transplantation. We searched the MEDLINE, EMBASE, The Cochrane Library, and PREMEDLINE databases for studies reporting thrombosis following pancreas transplantation. Identified publications were screened for inclusion and synthesized into a data extraction sheet. Sixty-three studies satisfied eligibility criteria: 39 cohort studies, 22 conference abstracts, and 2 meta-analyses. Newcastle-Ottawa Scale appraisal of included studies demonstrated cohort studies of low bias risk; 1127 thrombi were identified in 15 936 deceased donor, whole pancreas transplants, conferring a 7.07% overall thrombosis rate. Thrombosis resulted in pancreatic allograft loss in 83.3% of reported cases. This review has established significant associations between donor and recipient characteristics, procurement and preservation methodology, transplantation technique, postoperative management, and increased risk of early thrombosis in the pancreas allograft. Further studies examining the type of organ preservation fluid, prophylactic heparin protocol, and exocrine drainage method and early thrombosis should also be performed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.