ArticlePharmacoepidemiology and drug safety2020
Prevalence and incidence rate of hospital admissions related to medication between 2008 and 2013 in The Netherlands.
Article in Pharmacoepidemiology and drug safety, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The association between age and medication-related hospital admission in adults: a systematic review and meta-analysis.International journal of clinical pharmacy · 2026Pooled it
- Detectability of Medication Errors With a STOPP/START-Based Medication Review in Older People Prior to a Potentially Preventable Drug-Related Hospital Admission.Drug safety · 2022Trial
- The prevalence of medication-related hospital readmissions after bariatric surgery: a retrospective observational study.International journal of clinical pharmacy · 2026Observational
- Less Is More: Optimized pharmacotherapy with improved coNtinuity of CarE in hospitaLized oLder peOple (LIMONCELLO): study protocol of a cluster randomized controlled trial.BMC geriatrics · 2025Article
- Efficiency of computerized clinical decision support systems involving anticoagulants: A flashmob study in Dutch hospital pharmacies.British journal of clinical pharmacology · 2025Article
- The use of artificial intelligence to optimize medication alerts generated by clinical decision support systems: a scoping review.Journal of the American Medical Informatics Association : JAMIA · 2024Article
- Article
- Adherence to coprescribing of laxatives with opioids and associated characteristics in general practices in the Netherlands.BMC primary care · 2022Observational
- Feasibility of a protocol for deprescribing antihypertensive medication in older patients in Dutch general practices.BMC primary care · 2022Article
- Exploring the prevalence and characteristics of adverse drug events among older adults in South Korea using a national health insurance database.Frontiers in pharmacology · 2022Article
- A retrospective observational study of the use of gastroprotection for patients on dual antiplatelet therapy.The British journal of cardiology · 2022Article
- Home Care Patients' Experiences with Home Care Nurses' Support in Medication Adherence.Patient preference and adherence · 2021Article
- Prevalence and incidence rate of hospital admissions related to medication between 2008 and 2013 in The Netherlands.Pharmacoepidemiology and drug safety · 2020Article
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Authors and funding
14 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeIn 2009 a Dutch guideline was published containing recommendations to reduce Hospital Admissions Related to Medications (HARMs). This study aims to examine time-trends of HARMs and their potential preventability between 2008 and 2013 in The Netherlands.
methodsA retrospective prevalence study was conducted using the Dutch PHARMO Database Network. A semi-automated pre-selection was used to make a crude identification of possible HARMs of which four samples were selected. These were independently assessed with respect to causality and potential preventability by a physician and pharmacist. The results were stratified by age into 18-64 years and 65 years and older. For these groups the net prevalences and incidence rates of HARMs and potentially preventable HARMs were calculated for the years 2008, 2009, 2011 and 2013.
resultsFour samples of 467 (2008), 447 (2009), 446 (2011) and 408 (2013) admissions were assessed. The net prevalence of HARMs in the 18-64 years group was approximately four times smaller compared to the older group with a mean prevalence of 2.7% (95% confidence interval [CI]:2.4%-3.0%) and 10.2% (95%CI: 9.7%-10.7%) respectively. The potential preventability was 25.1% (18.4%-31.8%) and 48.3% (95%CI: 44.8%-51.8%), respectively. The prevalence of HARMs in both groups did not change significantly between 2008 and 2013 with 2.4% (95%CI: 1.9%-3.0%) and 10.0% (95%CI: 9.0%-11.0%) in 2008 and 3.1% (2.7%-3.5%) and 10.4% (95%CI: 9.4%-11.4%) in 2013, respectively.
conclusionDespite efforts to reduce HARMs, the prevalence did not decrease over time. Additional measures are therefore necessary, especially in the elderly population.
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