Evidence map›Paper›PMID 33051828›Full record

ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2021

Patient ambassador support in newly diagnosed patients with acute leukemia during treatment: a feasibility study.

Kristina Holmegaard Nørskov, Dorthe Overgaard, Jannie Boesen, Anne Struer, Sarah Elke Weber Due El-Azem, Anders Tolver, Kirsten Lomborg, Lars Kjeldsen, Mary Jarden

Registry-linked trialAbstract readMulticenter Study
In one paragraph

Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03493906 (Patient Ambassador Support in Newly Diagnosed Patients With Acute Leukemia During Treatment), which is not on this map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03493906 nacompletednot on this map

Patient Ambassador Support in Newly Diagnosed Patients With Acute Leukemia During Treatment: a Feasibility Study

TypeinterventionalSponsorRigshospitalet, DenmarkRan2018 to 2019Enrolled61ConditionsAcute LeukemiaArmsPatient Ambassador Support
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Exploring motivations of peer supporters for caregivers of patients with hematological malignancies-a qualitative study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kristina Holmegaard NørskovDepartment of Hematology, Rigshspitalet, Blegdamsvej 9, 2100, Copenhagen Ø, Denmark. Kristina.holmegaard.noerskov@regionh.dk.ORCID http://orcid.org/0000-0002-1055-9161
Dorthe OvergaardUniversity College Copenhagen, Tagensvej 18, 2200, Copenhagen N, Denmark.
Jannie BoesenDepartment of Hematology, Herlev Hospital, Borgmester Ib Juuls Vej 1, 2730, Herlev, Denmark.
Anne StruerDepartment of Hematology, Zealand University Hospital, Roskilde, Sygehusvej 10, 4000, Roskilde, Denmark.
Sarah Elke Weber Due El-AzemDepartment of Hematology, Zealand University Hospital, Roskilde, Sygehusvej 10, 4000, Roskilde, Denmark.
Anders TolverData Science Laboratory, Department of Mathematical Sciences, University of Copenhagen, Universitetsparken 5, 2200, Copenhagen N, Denmark.
Kirsten LomborgDepartment of Clinical Medicine, Aarhus University, Paalle Juul-Jensens Boulevard 82, 8200, Aarhus N, Denmark.
Lars KjeldsenDepartment of Hematology, Rigshspitalet, Blegdamsvej 9, 2100, Copenhagen Ø, Denmark.
Mary JardenDepartment of Hematology, Rigshspitalet, Blegdamsvej 9, 2100, Copenhagen Ø, Denmark.

Funding

Novo Nordisk Fonden (DK) NNF17OC0030072
6 · The paper itself

Abstract

purposeThis study investigated the feasibility of patient ambassador support in newly diagnosed patients with acute leukemia during treatment.

methodsA multicenter single-arm feasibility study that included patients newly diagnosed with acute leukemia (n = 36) and patient ambassadors previously treated for acute leukemia (n = 25). Prior to the intervention, all patient ambassadors attended a 6-h group training program. In the intervention, patient ambassadors provided 12 weeks of support for patients within 2 weeks of being diagnosed. Outcome measures included feasibility (primary outcome), safety, anxiety, and depression measured by the Hospital Anxiety and Depression Scale, quality of life by the Functional Assessment of Cancer Therapy-Leukemia and the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire, and symptom burden by MD Anderson Symptom Inventory, the Patient Activation Measure, and the General Self-Efficacy Scale.

resultsPatient ambassador support was feasible and safe in this population. Patients and patient ambassadors reported high satisfaction with the individually adjusted support, and patients improved in psychosocial outcomes over time. Patient ambassadors maintained their psychosocial baseline level, with no adverse events, and used the available support to exchange experiences with other patient ambassadors and to manage challenges.

conclusionThe patient ambassador support program is feasible and has the potential to be a new model of care incorporated in the hematology clinical care setting, creating an active partnership between patients and former patients. This may strengthen the existing supportive care services for patients with acute leukemia.

trial registrationNCT03493906.

Indexed as

Social SupportAdultAgedFeasibility StudiesFemaleHumansLeukemiaMaleMiddle AgedQuality of LifeYoung AdultAcute leukemiaFeasibilityPatient ambassadorPeer supportPsychosocialSupportive care

Identifiers

PMID33051828
PMCPMC8062400

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.