Evidence map›Paper›PMID 33051722›Full record

SynthesisAesthetic plastic surgery2021

Assessment of the Causes of Differences in Centrifugation Protocols as a Fat-Processing Technique: A Systematic Literature Review.

Oguzhan Demirel, Funda Aköz Saydam

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Aesthetic plastic surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Oguzhan DemirelDepartment of Plastic, Reconstructive, and Aesthetic Surgery, Denizli Devlet Hastanesi, Sırakapılar, Selcuk Caddesi, Merkezefendi, 20100, Denizli, Turkey. mdoguzhandemirel@gmail.com.ORCID http://orcid.org/0000-0001-5807-1758
Funda Aköz SaydamDepartment of Plastic, Reconstructive, and Aesthetic Surgery, Medicine Hospital, Barbaros, Hoca Ahmet Yesevi Cd. No: 149, 34203, Bağcılar, Istanbul, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCentrifugation has been widely used for fat graft processing. However, numerous different centrifugation protocols have been proposed in different studies. Investigation of these major differences is needed to clarify ambiguities and to achieve standardization. This review aimed to assess the causes of differences in centrifugation protocols as a fat-processing technique.

methodsFull-text and English-language articles between 1990 and 2020 were included in this study. Articles that assess the effect of centrifugation on fat graft survival with the following research purposes were selected: determination of the effect of centrifugation force/speed, determination of the effect of centrifugation time/duration, and comparison with other fat-processing techniques.

resultsFifty-four full-text, English-language articles were included. The number of articles that assessed centrifugation force/speed was 17 and centrifugation duration/time was 4, and the number of articles that compared centrifugation with other fat-processing techniques was 29 and centrifugation with noncentrifugation techniques was 4. Based on the study design, 25 experiments were performed in vivo, and 41 were performed in vitro.

conclusionMisuse of force (g) and speed (rpm) for defining the centrifugation protocol, differences in selected techniques for the graft harvest and graft transfer steps and differences in the analysis methods for fat graft survival are the main causes of these substantial variations among studies. LEVEL OF EVIDENCE III: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.

Indexed as

Adipose TissueGraft SurvivalCentrifugationHumansRisk AssessmentCentrifugeDurationFatForceGraftSpeedSurvivalTime

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.