ArticleScientific reports2020
Validation of a survival benefit estimator tool in a cohort of European kidney transplant recipients.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Using Information Available at the Time of Donor Offer to Predict Kidney Transplant Survival Outcomes: A Systematic Review of Prediction Models.Transplant international : official journal of the European Society for Organ Transplantation · 2022Pooled it
- Validation of Kidney Donor Profile Index and Estimated Post-Transplant Survival Scores in an Eastern European Transplantation Center-A Seven-Year Retrospective Observational Study.Journal of clinical medicine · 2025Article
- Kidney transplantation outcomes: Is it possible to improve when good results are falling down?World journal of transplantation · 2024Article
- An external validation of the Kidney Donor Risk Index in the UK transplant population in the presence of semi-competing events.Diagnostic and prognostic research · 2023Article
- Kidney Donor Profile Index and allograft outcomes: interactive effects of estimated post-transplant survival score and ischaemic time.Clinical kidney journal · 2023Article
- Predicting 5-year survival after kidney transplantation in Colombia using the survival benefit estimator tool.PloS one · 2023Article
- Artificial Intelligence-A Tool for Risk Assessment of Delayed-Graft Function in Kidney Transplant.Journal of clinical medicine · 2021Article
- Development of predictive score for post-transplant survival based on pre-transplant recipient characteristics.Korean journal of transplantation · 2021Article
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pre-transplant prognostic scores help to optimize donor/recipient allocation and to minimize organ discard rates. Since most of these scores come from the US, direct application in non-US populations is not advisable. The Survival Benefit Estimator (SBE), built upon the Estimated Post-Transplant Survival (EPTS) and the Kidney Donor Profile Index (KDPI), has not been externally validated. We aimed to examine SBE in a cohort of Spanish kidney transplant recipients. We designed a retrospective cohort-based study of deceased-donor kidney transplants carried out in two different Spanish hospitals. Unadjusted and adjusted Cox models were applied for patient survival. Predictive models were compared using Harrell's C statistics. SBE, EPTS and KDPI were independently associated with patient survival (p ≤ 0.01 in all models). Model discrimination measured with Harrell's C statistics ranged from 0.57 (KDPI) to 0.69 (SBE) and 0.71 (EPTS). After adjustment, SBE presented similar calibration and discrimination power to that of EPTS. SBE tended to underestimate actual survival, mainly among high EPTS recipients/high KDPI donors. SBE performed acceptably well at discriminating post-transplant survival in a cohort of Spanish deceased-donor kidney transplant recipients, although its use as the main allocation guide, especially for high KDPI donors or high EPTS recipients requires further testing.
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