ArticleScientific reports2020
Healthcare resources attributable to methicillin-resistant Staphylococcus aureus orthopedic surgical site infections.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
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- Postoperative risks of type 2 diabetes in elderly hip fracture patients: a propensity score-matched study.Journal of bone and mineral metabolism · 2025Article
- Multifunctional 3D-Printed Wound Dressings Containing a Combination of Synergistic Antimicrobials in the Management of MRSA Infected Topical Wounds.ACS applied materials & interfaces · 2025Article
- Seasonality and Trend of Cellulitis, Herpes Zoster, and Varicella: A Nationwide Population-based Study.JMA journal · 2025Article
- Biocompatibility and antimicrobial efficacy of iodine-supported titania nanotubes on 3D-printed Ti-6Al-4V implants.PloS one · 2025Article
- Article
- Burden of Antimicrobial Resistance in Japan: A Systematic Literature Review and Meta-Analysis.Infectious diseases and therapy · 2024Article
- Incidence of surgical site infection after internal fixation of the first phalangeal bone and the third metacarpal/metatarsal bone fractures in Thoroughbred racehorses.Journal of equine science · 2023Article
- The Role of the Gut Microbiome on the Development of Surgical Site Infections.Clinics in colon and rectal surgery · 2023Review
- Staphylococcus aureus populations from the gut and the blood are not distinguished by virulence traits-a critical role of host barrier integrity.Microbiome · 2022Article
- Effectiveness of Extended Infection Control Measures on Methicillin-ResistantIndian journal of orthopaedics · 2022Article
- Comparison of Antimicrobial Activity Between Bacitracin-Soaked Sutures and Triclosan Coated Suture.The Journal of surgical research · 2022Article
- Staphylococcal trafficking and infection-from 'nose to gut' and back.FEMS microbiology reviews · 2022Review
- Influence of chitosan and chitosan oligosaccharide on dual antibiotic-loaded bone cement: In vitro evaluations.PloS one · 2022Article
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The number of orthopedic surgeries is increasing as populations steadily age, but surgical site infection (SSI) rates remain relatively consistent. This study aimed to quantify the healthcare resources attributable to methicillin-resistant Staphylococcus aureus (MRSA) SSIs in orthopedic surgical patients. The analysis was conducted using a national claims database comprising data from almost all Japanese residents. We examined patients who underwent any of the following surgeries between April 2012 and March 2018: amputation (AMP), spinal fusion (FUSN), open reduction of fracture (FX), hip prosthesis (HPRO), knee prosthesis (KPRO), and laminectomy (LAM). Propensity score matching was performed to identify non-SSI control patients, and generalized estimating equations were used to estimate the differences in outcomes between the case and control groups. The numbers of MRSA SSI cases (infection rates) ranged from 64 (0.03%) to 1,152 (2.33%). MRSA SSI-attributable increases in healthcare expenditure ranged from $11,630 ($21,151 vs. $9,521) for LAM to $35,693 ($50,122 vs. $14,429) for FX, and increases in hospital stay ranged from 40.6 days (59.2 vs. 18.6) for LAM to 89.5 days (122.0 vs. 32.5) for FX. In conclusion, MRSA SSIs contribute to substantial increases in healthcare resource utilization, emphasizing the need to implement effective infection prevention measures for orthopedic surgeries.
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