Evidence map›Paper›PMID 33051471›Full record

ArticleScientific reports2020

Bundle analytics, a computational framework for investigating the shapes and profiles of brain pathways across populations.

Bramsh Qamar Chandio, Shannon Leigh Risacher, Franco Pestilli, Daniel Bullock, Fang-Cheng Yeh, Serge Koudoro, Ariel Rokem, Jaroslaw Harezlak, Eleftherios Garyfallidis

Abstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers.

0numbers the graph read from it
0cells of the map it votes in
72citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

72 citing papers in PubMed.

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  19. Logarithmic kinetics and bundling in random packings of elongated 3D physical links.Proceedings of the National Academy of Sciences of the United States of America · 2025
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12 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Bramsh Qamar ChandioDepartment of Intelligent Systems Engineering, Luddy School of Informatics, Computing and Engineering, Indiana University Bloomington, Bloomington, IN, USA. bqchandi@iu.edu.
Shannon Leigh RisacherIndiana University School of Medicine, Indianapolis, IN, USA.
Franco PestilliDepartment of Psychology, The University of Texas, Austin, TX, USA.
Daniel BullockDepartment of Psychological and Brain Sciences, Indiana University Bloomington, Bloomington, IN, USA.
Fang-Cheng YehDepartment of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA, USA.
Serge KoudoroDepartment of Intelligent Systems Engineering, Luddy School of Informatics, Computing and Engineering, Indiana University Bloomington, Bloomington, IN, USA.
Ariel RokemDepartment of Psychology and eScience Institute, University of Washington, Washington, DC, USA.
Jaroslaw HarezlakSchool of Public Health, Indiana University Bloomington, Bloomington, IN, USA.
Eleftherios GaryfallidisDepartment of Intelligent Systems Engineering, Luddy School of Informatics, Computing and Engineering, Indiana University Bloomington, Bloomington, IN, USA.

Funding

CRCNS: Community-supported open-source software for computational neuroanatomyR01EB027585 · NIBIB · TRUSTEES OF INDIANA UNIVERSITY · PI Eleftherios Garyfallidis · 2018 to 2026
$2.6M
Statistical models for multi-modal brain imaging studies of HIV-associated cognitive declineR01MH108467 · NIMH · INDIANA UNIVERSITY INDIANAPOLIS · PI HAREZLAK, JAROSLAW · 2015 to 2019
$2.0M
NIBIB NIH HHS R01 EB027585NIH HHS R01EB027585NIMH NIH HHS R01MH108467
6 · The paper itself

Abstract

Tractography has created new horizons for researchers to study brain connectivity in vivo. However, tractography is an advanced and challenging method that has not been used so far for medical data analysis at a large scale in comparison to other traditional brain imaging methods. This work allows tractography to be used for large scale and high-quality medical analytics. BUndle ANalytics (BUAN) is a fast, robust, and flexible computational framework for real-world tractometric studies. BUAN combines tractography and anatomical information to analyze the challenging datasets and identifies significant group differences in specific locations of the white matter bundles. Additionally, BUAN takes the shape of the bundles into consideration for the analysis. BUAN compares the shapes of the bundles using a metric called bundle adjacency which calculates shape similarity between two given bundles. BUAN builds networks of bundle shape similarities that can be paramount for automating quality control. BUAN is freely available in DIPY. Results are presented using publicly available Parkinson's Progression Markers Initiative data.

Indexed as

Data AnalysisDiffusion Tensor ImagingHumansImage Processing, Computer-AssistedNeural PathwaysNeuroimagingQuality ControlWhite Matter

Identifiers

PMID33051471
PMCPMC7555507

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.