Evidence map›Paper›PMID 33051367›Full record

ArticlemBio2020

Sensing Host Arginine Is Essential for

Adele Goldman-Pinkovich, Sriram Kannan, Roni Nitzan-Koren, Madhu Puri, Harsh Pawar, Yael Bar-Avraham, Jacquelyn McDonald, Aakash Sur, Wen-Wei Zhang, Greg Matlashewski and 4 more

Open access · goldAbstract read
In one paragraph

Article in mBio, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 25 citations in OpenAlex.

  1. Review
  2. Frontiers in immunology · 2026
    Review
  3. Article
  4. Deciphering Host-Parasite Interplay inACS infectious diseases · 2024
    Article
  5. Review
  6. Synthetic biology for combating leishmaniasis.Frontiers in microbiology · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. Polyamine Metabolism inMedical sciences (Basel, Switzerland) · 2022
    Review
  11. Article
  12. Review
  13. Article
  14. Lysosome Sensing Is a Key Mechanism inFrontiers in microbiology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 4 countries.

Adele Goldman-PinkovichFaculty of Biology, Technion-Israel Institute of Technology, Haifa, Israel.
Sriram KannanThe Mina and Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan, Israel.
Roni Nitzan-KorenFaculty of Biology, Technion-Israel Institute of Technology, Haifa, Israel.
Madhu PuriSchool of Life Sciences, Jawaharlal Nehru University, New Delhi, India.
Harsh PawarFaculty of Biology, Technion-Israel Institute of Technology, Haifa, Israel.
Yael Bar-AvrahamFaculty of Biology, Technion-Israel Institute of Technology, Haifa, Israel.
Jacquelyn McDonaldCenter for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, Washington, USA.
Aakash SurDepartment of Biomedical Informatics and Medical Education, University of Washington, Seattle, Washington, USA.
Wen-Wei ZhangDepartment of Microbiology and Immunology, McGill University, Montreal, Canada.
Greg MatlashewskiDepartment of Microbiology and Immunology, McGill University, Montreal, Canada.ORCID 0000-0002-8971-5525
Rentala MadhubalaSchool of Life Sciences, Jawaharlal Nehru University, New Delhi, India.
Shulamit MichaeliThe Mina and Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan, Israel.
Peter J MylerCenter for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, Washington, USA.
Dan ZilbersteinFaculty of Biology, Technion-Israel Institute of Technology, Haifa, Israel danz@technion.ac.il.ORCID 0000-0002-8237-9717
Technion – Israel Institute of Technology · ILBar-Ilan University · ILInfectious Disease Research Institute · USJawaharlal Nehru University · INMcGill University · CAUniversity of Washington Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Arginine homeostasis in lysosomes is critical for the growth and metabolism of mammalian cells. Phagolysosomes of macrophages are the niche where the parasitic protozoan

Indexed as

Host-Parasite InteractionsAnimalsArginineCRISPR-Cas SystemsFemaleLeishmaniaLeishmaniasisLysosomesMacrophagesMembrane Transport ProteinsMiceMice, Inbred BALB CPhagosomesArginineMembrane Transport Proteinsamino acid sensingamino acid transporthost-pathogen interactionintracellular parasitismLeishmania

Identifiers

PMID33051367
PMCPMC7554669
OpenAlexW3092077289

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.