Evidence map›Paper›PMID 33051347›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2020

The Neurokinin-1 Receptor is Expressed with Gastrin-Releasing Peptide Receptor in Spinal Interneurons and Modulates Itch.

Tayler D Sheahan, Charles A Warwick, Louis G Fanien, Sarah E Ross

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 32 citations in OpenAlex.

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  20. The Spino-Parabrachial Pathway for Itch.Frontiers in neural circuits · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Tayler D SheahanPittsburgh Center for Pain Research and Department of Neurobiology, University of Pittsburgh, Pittsburgh 15213, Pennsylvania.ORCID 0000-0002-5015-0600
Charles A WarwickPittsburgh Center for Pain Research and Department of Neurobiology, University of Pittsburgh, Pittsburgh 15213, Pennsylvania.ORCID 0000-0001-6244-9821
Louis G FanienPittsburgh Center for Pain Research and Department of Neurobiology, University of Pittsburgh, Pittsburgh 15213, Pennsylvania.
Sarah E RossPittsburgh Center for Pain Research and Department of Neurobiology, University of Pittsburgh, Pittsburgh 15213, Pennsylvania saross@pitt.edu.
University of Pittsburgh · US

Funding

Investigating the Neural Circuits of ItchR01AR063772 · NIAMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI H Richard Koerber, Sarah Elizabeth Ross · 2013 to 2026
$6.9M
Molecular genetic dissection of the spinal microcircuits of wind-upR01NS096705 · NINDS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KOERBER, H RICHARD, ROSS, SARAH ELIZABETH · 2016 to 2025
$5.1M
Training in the Neurobiology of Neurological DiseaseT32NS086749 · NINDS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Omar El Gharbawie, REBECCA P SEAL · 2014 to 2026
$4.8M
Training in Mechanisms and Clinical Presentation of PainT32NS073548 · NINDS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Jami Lynn Saloman, BRADLEY K. TAYLOR · 2012 to 2026
$3.1M
Understanding spinal neuropeptide signaling in itchR00NS126569 · NINDS · MEDICAL COLLEGE OF WISCONSIN · PI Tayler Sheahan · 2025 to 2026
$498k
Understanding the spinal circuitry of coldF32NS110155 · NINDS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SHEAHAN, TAYLER · 2018 to 2021
$225k
NIAMS NIH HHS R01 AR063772NINDS NIH HHS F32 NS110155NINDS NIH HHS L30 NS113129NINDS NIH HHS R00 NS126569NINDS NIH HHS R01 NS096705NINDS NIH HHS T32 NS073548NINDS NIH HHS T32 NS086749
6 · The paper itself

Abstract

The neurokinin-1 receptor (NK1R; encoded by

Indexed as

InterneuronsAdultAnimalsBehavior, AnimalBrachial PlexusFemaleHumansMaleMice, Inbred C57BLMiddle AgedNerve NetPainPosterior Horn CellsPruritusReceptors, BombesinReceptors, Neurokinin-1Receptors, BombesinReceptors, Neurokinin-1dorsal hornGRPRNK1Rprojection neuronsspinal circuitryspinal cord

Identifiers

PMID33051347
PMCPMC7659450
OpenAlexW3091974208

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.