Evidence map›Paper›PMID 33051260›Full record

ArticleG3 (Bethesda, Md.)2020

Maintenance of Cell Fate by the Polycomb Group Gene Sex Combs Extra Enables a Partial Epithelial Mesenchymal Transition in

Grace Jefferies, Jason Somers, Isabelle Lohrey, Vishal Chaturvedi, Jacob Calabria, Owen J Marshall, Tony D Southall, Robert Saint, Michael J Murray

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in G3 (Bethesda, Md.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 90% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Grace JefferiesSchool of BioSciences, University of Melbourne, Melbourne, VIC, Australia.ORCID 0000-0002-3643-6733
Jason SomersSchool of BioSciences, University of Melbourne, Melbourne, VIC, Australia.ORCID 0000-0001-8992-344X
Isabelle LohreySchool of BioSciences, University of Melbourne, Melbourne, VIC, Australia.
Vishal ChaturvediSchool of BioSciences, University of Melbourne, Melbourne, VIC, Australia.ORCID 0000-0002-0421-7544
Jacob CalabriaSchool of BioSciences, University of Melbourne, Melbourne, VIC, Australia.
Owen J MarshallMenzies Institute for Medical Research, University of Tasmania, Hobart, TAS, Australia.ORCID 0000-0003-1605-3871
Tony D SouthallImperial College London, Sir Ernst Chain Building, South Kensington Campus, London, UK.ORCID 0000-0002-8645-4198
Robert SaintSchool of BioSciences, University of Melbourne, Melbourne, VIC, Australia.ORCID 0000-0002-7989-6043
Michael J MurraySchool of BioSciences, University of Melbourne, Melbourne, VIC, Australia murraym@unimelb.edu.au.ORCID 0000-0002-7427-590X
University of Melbourne · AUImperial College London · GBUniversity of Tasmania · AU

Funding

Wellcome TrustWellcome Trust 104567/Z/14/Z
6 · The paper itself

Abstract

Epigenetic silencing by Polycomb group (PcG) complexes can promote epithelial-mesenchymal transition (EMT) and stemness and is associated with malignancy of solid cancers. Here we report a role for

Indexed as

DrosophilaDrosophila ProteinsPolycomb-Group ProteinsAnimalsEpithelial-Mesenchymal TransitionPolycomb Repressive Complex 1Drosophila ProteinsPolycomb-Group ProteinsPolycomb Repressive Complex 1Sce protein, DrosophilaSCM protein, DrosophilaAbdominal BDrosophilaepigeneticsepithelial mesenchymal transitionPolycomb GroupSex combs extraTargeted DamIDwing eversion

Identifiers

PMID33051260
PMCPMC7718746
OpenAlexW3092504938

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.