Evidence map›Paper›PMID 33051002›Full record

ArticleeLife2020

Cytoplasmic sharing through apical membrane remodeling.

Nora G Peterson, Benjamin M Stormo, Kevin P Schoenfelder, Juliet S King, Rayson Rs Lee, Donald T Fox

Open access · goldAbstract read
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Cell-cell fusion: To lose one life and begin another.BioEssays : news and reviews in molecular, cellular and developmental biology · 2025
    Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Communal living: the role of polyploidy and syncytia in tissue biology.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2021
    Review
  12. Polyploidy in Tissue Repair and Regeneration.Cold Spring Harbor perspectives in biology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Nora G PetersonDepartment of Cell Biology, Duke University Medical Center, Durham, United States.ORCID 0000-0002-7734-1861
Benjamin M StormoDepartment of Cell Biology, Duke University Medical Center, Durham, United States.ORCID 0000-0002-6861-8451
Kevin P SchoenfelderUniversity Program in Genetics and Genomics, Duke University, Durham, United States.
Juliet S KingDepartment of Pharmacology & Cancer Biology, Duke University Medical Center, Durham, United States.
Rayson Rs LeeDuke-NUS Medical School, Singapore, Singapore.
Donald T FoxDepartment of Cell Biology, Duke University Medical Center, Durham, United States.ORCID 0000-0002-0436-179X
Duke University · USDuke Medical Center · USDuke-NUS Medical School · SG

Funding

ORGANIZATION AND FUNCTIONS OF CELLULAR STRUCTUREST32GM007184 · NIGMS · DUKE UNIVERSITY · PI JINKS-ROBERTSON, SUE · 1985 to 2019
$18.2M
Training Program in Developmental & Stem Cell BiologyT32HD040372 · NICHD · DUKE UNIVERSITY · PI Terry H Lechler · 2001 to 2026
$8.9M
Polyploidy after tissue injury: a Drosophila modelR01GM118447 · NIGMS · DUKE UNIVERSITY · PI FOX, DONALD T. · 2016 to 2025
$3.1M
Polyploidy in Cardiac Development and Tissue Repair in DrosophilaF31HL140811 · NHLBI · DUKE UNIVERSITY · PI PETERSON, NORA GRACE · 2018 to 2020
$118k
NHLBI NIH HHS F31 HL140811NICHD NIH HHS T32 HD040372NIGMS NIH HHS R01 GM118447NIGMS NIH HHS T32 GM007184NIH HHS GM118447
6 · The paper itself

Abstract

Multiple nuclei sharing a common cytoplasm are found in diverse tissues, organisms, and diseases. Yet, multinucleation remains a poorly understood biological property. Cytoplasm sharing invariably involves plasma membrane breaches. In contrast, we discovered cytoplasm sharing without membrane breaching in highly resorptive

Indexed as

AnimalsCell MembraneConnexinsCrosses, GeneticCytokinesisCytoplasmCytosolDrosophila melanogasterEpitheliumGap JunctionsGenotypeGTP PhosphohydrolasesIntestinesMicroscopy, Electron, TransmissionSignal TransductionConnexinsGTP Phosphohydrolasesdevelopmental biologyD. melanogasterdynamingap junctionsmultinucleate

Identifiers

PMID33051002
PMCPMC7655102
OpenAlexW3091808654

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.