Evidence map›Paper›PMID 33050687›Full record

ArticleUltrasonography (Seoul, Korea)2021

Key imaging features for differentiating cystic biliary atresia from choledochal cyst: prenatal ultrasonography and postnatal ultrasonography and MRI.

Hyun Joo Shin, Haesung Yoon, Seok Joo Han, Kyong Ihn, Hong Koh, Ja-Young Kwon, Mi-Jung Lee

Open access · diamondAbstract read
In one paragraph

Article in Ultrasonography (Seoul, Korea), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
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  5. Article
  6. Article
  7. Article
  8. Article
  9. Giant bile duct dilatation in newborn: A case report.World journal of clinical cases · 2024
    Article
  10. Article
  11. [Diagnostic Imaging of Biliary Atresia].Journal of the Korean Society of Radiology · 2022
    Review
  12. [Overview of Biliary Atresia].Journal of the Korean Society of Radiology · 2022
    Review
  13. Imaging of fibropolycystic liver disease.Abdominal radiology (New York) · 2022
    Review
  14. Review
  15. Article
  16. Review
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Hyun Joo ShinDepartment of Radiology, Severance Hospital, Research Institute of Radiological Science, Seoul, Korea.
Haesung YoonDepartment of Radiology, Severance Hospital, Research Institute of Radiological Science, Seoul, Korea.
Seok Joo HanSeverance Pediatric Liver Disease Research Group, Institute of Women's Life Medical Science, Yonsei University College of Medicine, Seoul, Korea.
Kyong IhnSeverance Pediatric Liver Disease Research Group, Institute of Women's Life Medical Science, Yonsei University College of Medicine, Seoul, Korea.
Hong KohSeverance Pediatric Liver Disease Research Group, Institute of Women's Life Medical Science, Yonsei University College of Medicine, Seoul, Korea.
Ja-Young KwonDivision of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Institute of Women's Life Medical Science, Yonsei University College of Medicine, Seoul, Korea.
Mi-Jung LeeDepartment of Radiology, Severance Hospital, Research Institute of Radiological Science, Seoul, Korea.
Yonsei University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study compared clinical and radiologic differences between cystic biliary atresia (cBA) and choledochal cyst (CC) type Ia/b.

methodsInfants (≤12 months old) who were diagnosed with cBA or CC type Ia/b from 2005 to 2019 were retrospectively reviewed. Imaging features on preoperative ultrasonography (US) and magnetic resonance imaging (MRI) were compared between the cBA and CC groups. Logistic regression and area under the receiver operating characteristic curve (AUC) analyses were performed for the diagnosis of cBA. Changes in cyst size were also evaluated when prenatal US exams were available.

resultsTen patients (5.5% of biliary atresia cases) with cBA (median age, 48 days) and 11 infants with CC type Ia/b (Ia:Ib=10:1; median age, 20 days) were included. Triangular cord thickness on US (cutoff, 4 mm) showed 100% sensitivity and 90.9% specificity (AUC, 0.964; 95% confidence interval [CI], 0.779 to 1.000) and cyst size on MRI (cutoff, 2.2 cm) had 70% sensitivity and 100% specificity (AUC, 0.900; 95% CI, 0.690 to 0.987) for diagnosing cBA. Gallbladder mucosal irregularity on US and an invisible distal common bile duct on MRI were only seen in the cBA group (10 of 10). Only the CC group showed prenatal cysts exceeding 1 cm with postnatal enlargement.

conclusionSmall cyst size (<1 cm) on prenatal US, triangular cord thickening (≥4 mm) and gallbladder mucosal irregularity on postnatal US, and small cyst size (≤2.2 cm) and an invisible distal common bile duct on MRI can discriminate cBA from CC type Ia/b in infancy.

Indexed as

Biliary atresiaCholedochal cystMagnetic resonance imagingNeonatal jaundiceUltrasonography

Identifiers

PMID33050687
PMCPMC7994739
OpenAlexW3046796681

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.