Evidence map›Paper›PMID 33050602›Full record

ReviewMolecules (Basel, Switzerland)2020

Antibody-Targeted Imaging of Gastric Cancer.

Komal Mandleywala, Shayla Shmuel, Patricia M R Pereira, Jason S Lewis

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Komal MandleywalaDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Shayla ShmuelDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Patricia M R PereiraDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.ORCID 0000-0002-4772-9339
Jason S LewisDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.ORCID 0000-0001-7065-4534
Memorial Sloan Kettering Cancer Center · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
Leveraging Pb-203/212 for the Theranostic Imaging and Therapy of Prostate CancerR35CA232130 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI LEWIS, JASON S. · 2019 to 2025
$8.2M
Alan and Sandra Gerry Metastasis and Tumor Ecosystems Center N/AGeoffrey Beene Cancer Research Center (JSL) N/ANCI NIH HHS P30 CA008748NCI NIH HHS R35 CA232130Tow Foundation (PMRP) N/A
6 · The paper itself

Abstract

The specificity of antibodies for antigens overexpressed or uniquely expressed in tumor cells makes them ideal candidates in the development of bioconjugates for tumor imaging. Molecular imaging can aid clinicians in the diagnosis of gastric tumors and in selecting patients for therapies targeting receptors with a heterogeneous intratumoral or intertumoral expression. Antibodies labeled with an imaging radiometal can be used to detect primary tumors and metastases using whole-body positron emission tomography (PET) or single photon emission computed tomography (SPECT), both during diagnosis and monitoring disease response. Conjugated with fluorescent dyes, antibodies can image tumors by targeted optical imaging. This review provides an overview of the most recent advances in the use of antibodies labeled with radiometals or conjugated with fluorescent dyes for gastric cancer imaging.

Indexed as

AnimalsHumansOptical ImagingPositron-Emission TomographyStomach NeoplasmsTomography, Emission-Computed, Single-Photongastric cancermolecular imagingoptical imagingPETSPECT

Identifiers

PMID33050602
PMCPMC7587187
OpenAlexW3092255185

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.