Evidence map›Paper›PMID 33050574›Full record

SynthesisInternational journal of environmental research and public health2020

A Systematic Review and Meta-Analysis of Hospitalised Current Smokers and COVID-19.

Jesus González-Rubio, Carmen Navarro-López, Elena López-Nájera, Ana López-Nájera, Lydia Jiménez-Díaz, Juan D Navarro-López, Alberto Nájera

Open access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in International journal of environmental research and public health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
7.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it, 67 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Observational
  8. Article
  9. The controversial effect of smoking and nicotine in SARS-CoV-2 infection.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2023
    Review
  10. Review
  11. E-Cigarette Vapour Increases ACE2 and TMPRSS2 Expression in a Flavour- and Nicotine-Dependent Manner.International journal of environmental research and public health · 2022
    Article
  12. Observational
  13. Article
  14. ASSOCIATION OF SMOKING AND SEVERITY OF COVID-19 INFECTION AMONG 5,889 PATIENTS IN MALAYSIA: A MULTI-CENTER OBSERVATIONAL STUDY.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2022
    Observational
  15. Article
  16. Article
  17. Article
  18. Smoking and COVID-19 in ICU Patients.Medical archives (Sarajevo, Bosnia and Herzegovina) · 2021
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Jesus González-RubioSchool of Medicine, CRIB, University of Castilla-La Mancha, 02008 Albacete, Spain.ORCID 0000-0002-9914-2505
Carmen Navarro-LópezHospital General La Mancha Centro, Servicio de Salud de Castilla-La Mancha, Alcazar de San Juan, 13600 Ciudad Real, Spain.
Elena López-NájeraGerencia de Atención Primaria, Salud de Castilla y Leon, 05003 Avila, Spain.
Ana López-NájeraGerencia de Emergencias Sanitarias, 47407 Salud de Castilla y Leon, Spain.
Lydia Jiménez-DíazCentre for Biomedical Research, School of Medicine, University of Castilla-La Mancha, 13071 Ciudad Real, Spain.ORCID 0000-0001-9121-0334
Juan D Navarro-LópezCentre for Biomedical Research, School of Medicine, University of Castilla-La Mancha, 13071 Ciudad Real, Spain.ORCID 0000-0002-1877-7833
Alberto NájeraSchool of Medicine, CRIB, University of Castilla-La Mancha, 02008 Albacete, Spain.ORCID 0000-0002-9939-6003
University of Castilla-La Mancha · ESCentro de Emergencias Sanitarias 061 · ESJunta de Castilla y León · ESServicio de Salud de Castilla La Mancha · ES

Funding

Universidad de Castilla-La Mancha : 2020-GRIN-28705
6 · The paper itself

Abstract

SARS-CoV-2 is a new coronavirus that has caused a worldwide pandemic. It produces severe acute respiratory disease (COVID-19), which is fatal in many cases, characterised by the cytokine release syndrome (CRS). According to the World Health Organization, those who smoke are likely to be more vulnerable to infection. Here, in order to clarify the epidemiologic relationship between smoking and COVID-19, we present a systematic literature review until 28th April 2020 and a meta-analysis. We included 18 recent COVID-19 clinical and epidemiological studies based on smoking patient status from 720 initial studies in China, the USA, and Italy. The percentage of hospitalised current smokers was 7.7% (95% CI: 6.9-8.4) in China, 2.3% (95% CI: 1.7-2.9) in the USA and 7.6% (95% CI: 4.2-11.0) in Italy. These percentages were compared to the smoking prevalence of each country and statistically significant differences were found in them all (

Indexed as

ChinaCoronavirus InfectionsCOVID-19HospitalizationHumansItalyPandemicsPneumonia, ViralSmokersUnited Statescholinergic anti-inflammatory pathwayCOVID-19current smokerscytokine release syndrome (CRS)nicotineSARS-CoV-2

Identifiers

PMID33050574
PMCPMC7601505
OpenAlexW3092472768

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.