Evidence map›Paper›PMID 33050407›Full record

ReviewBiomolecules2020

Bullous Pemphigoid: Trigger and Predisposing Factors.

Francesco Moro, Luca Fania, Jo Linda Maria Sinagra, Adele Salemme, Giovanni Di Zenzo

Open access · goldAbstract readReview
In one paragraph

Review in Biomolecules, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 105 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
105citing papers in PubMed, 4 pooled it
12.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

105 citing papers in PubMed, 4 syntheses or guidelines pooled it, 160 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Selective Expansion of TCR Vβ2Experimental dermatology · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Bullous pemphigoid following adjuvant radiotherapy for breast cancer: a case report.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2026
    Article
  11. Article
  12. Article
  13. Article
  14. Secondary Syphilis With Concomitant Bullous Pemphigoid: A Case Report.Case reports in dermatological medicine · 2026
    Article
  15. Article
  16. Article
  17. Article
  18. A Case of Nivolumab-Induced Bullous Pemphigoid-Successfully Treated with Rituximab.Journal of community hospital internal medicine perspectives · 2026
    Article
  19. Association ofInternational journal of molecular sciences · 2025
    Article
  20. Article

45 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Luca Fania
Jo Linda Maria SinagraIDI-IRCCS, via dei Monti di Creta 104, 00167 Rome, Italy.
Adele SalemmeIDI-IRCCS, via dei Monti di Creta 104, 00167 Rome, Italy.
Giovanni Di ZenzoIDI-IRCCS, via dei Monti di Creta 104, 00167 Rome, Italy.
Istituto Dermopatico dell'Immacolata · IT

Funding

Italian Ministry of Health, Rome, Italy "Progetto Ricerca Corrente - 2019" and "Ricerca Finalizzata-2020"
6 · The paper itself

Abstract

Bullous pemphigoid (BP) is the most frequent autoimmune subepidermal blistering disease provoked by autoantibodies directed against two hemidesmosomal proteins: BP180 and BP230. Its pathogenesis depends on the interaction between predisposing factors, such as human leukocyte antigen (HLA) genes, comorbidities, aging, and trigger factors. Several trigger factors, such as drugs, thermal or electrical burns, surgical procedures, trauma, ultraviolet irradiation, radiotherapy, chemical preparations, transplants, and infections may induce or exacerbate BP disease. Identification of predisposing and trigger factors can increase the understanding of BP pathogenesis. Furthermore, an accurate anamnesis focused on the recognition of a possible trigger factor can improve prognosis by promptly removing it.

Indexed as

CausalityComorbidityDisease SusceptibilityDrug-Related Side Effects and Adverse ReactionsGene-Environment InteractionGenetic Predisposition to DiseaseHLA AntigensHumansInfectionsPemphigoid, BullousPrognosisRisk FactorsHLA Antigensautoimmune bullous diseasebullous pemphigoidetiopathogenesispredisposing factorstrigger factors

Identifiers

PMID33050407
PMCPMC7600534
OpenAlexW3092020794

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.