Evidence map›Paper›PMID 33050340›Full record

ArticleBrain sciences2020

Feasibility and Safety of Transcranial Direct Current Stimulation in an Outpatient Rehabilitation Setting After Stroke.

Brice T Cleland, Melissa Galick, Amy Huckstep, Laura Lenhart, Sangeetha Madhavan

Registry-linked trialAbstract read
In one paragraph

Article in Brain sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05582616 (The Safety and Feasibility of Transcranial Direct Current Stimulation Combined With Conservative Treatment for Cervicogenic Headaches), which is not on this map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05582616 nacompletednot on this mapstarted 2022, after this paper: background citation

The Safety and Feasibility of Transcranial Direct Current Stimulation Combined With Conservative Treatment for Cervicogenic Headaches

TypeinterventionalSponsorUniversity of CalgaryRan2022 to 2024Enrolled32ConditionsCervicogenic HeadacheArmsTranscranial Direct Current Stimulation, Sham Transcranial Direct Current Stimulation
3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Effects of Transcranial Direct Current Stimulation and Individualized Physical Therapy on Pain and Function in Individuals With Chronic Knee Pain: A Pilot Study.Physiotherapy research international : the journal for researchers and clinicians in physical therapy · 2026
    Trial
  2. Trial
  3. Trial
  4. Trial
  5. Neuroimmune Mechanisms and Emerging Intervention Strategies for Post-Stroke Fatigue: A Narrative Review.Medical science monitor : international medical journal of experimental and clinical research · 2026
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Brice T ClelandBrain Plasticity Lab, Department of Physical Therapy, College of Applied Health Sciences, University of Illinois at Chicago, Chicago, IL 60612, USA.
Melissa GalickShirley Ryan AbilityLab DayRehab Center, Homewood, IL 60430, USA.
Amy HuckstepShirley Ryan AbilityLab DayRehab Center, Homewood, IL 60430, USA.
Laura LenhartShirley Ryan AbilityLab DayRehab Center, Homewood, IL 60430, USA.
Sangeetha MadhavanBrain Plasticity Lab, Department of Physical Therapy, College of Applied Health Sciences, University of Illinois at Chicago, Chicago, IL 60612, USA.ORCID 0000-0001-6086-0027

Funding

Cortical priming to optimize gait rehabilitation post strokeR01HD075777 · NICHD · UNIVERSITY OF ILLINOIS AT CHICAGO · PI MADHAVAN, SANGEETHA · 2014 to 2024
$4.1M
Eunice Kennedy Shriver National Institute of Child Health and Human Development R01HD075777NICHD NIH HHS R01 HD075777Shirley Ryan AbilityLab James Brown IV Fellowship
6 · The paper itself

Abstract

Transcranial direct current stimulation (tDCS) has strong potential for outpatient clinical use, but feasibility and safety of tDCS has only been evaluated in laboratory and inpatient clinical settings. The objective of this study was to assess feasibility and safety of tDCS for stroke in an outpatient clinical setting. Individuals with stroke in outpatient therapy received tDCS during physical therapy sessions. Feasibility was assessed with screening, enrollment, withdrawal, and adherence numbers, tDCS impressions, and perceived benefits and detriments of tDCS. Acute changes in fatigue and self-reported function and pre-post changes in fatigue were also assessed. Safety was assessed as adverse events and side effects. In total, 85 individuals were screened, and 10 were enrolled. Most exclusions were unrelated to clinical feasibility. In total, 3 participants withdrew, so 7 participants completed 2 sessions/week for 5-6 weeks with 100% adherence. In total, 71% reported positive impressions of tDCS. tDCS setup decreased to 5-7 min at end of study. There was one adverse event unrelated to tDCS. Mild to moderate side effects (tingling, itching, pinching, and fatigue) were experienced. In total, 86% of participants recounted benefits of tDCS. There were acute improvements in function and energy. Results support the feasibility and safety of tDCS in an outpatient clinical setting.

Indexed as

day care, medicalequipment safetyfeasibility studiesneuroplasticitystroke rehabilitationtranscranial direct current stimulation

Identifiers

PMID33050340
PMCPMC7599981

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.