Evidence map›Paper›PMID 33050321›Full record

Trial reportNutrients2020

Brief Hospital Supervision of Exercise and Diet During Adjuvant Breast Cancer Therapy Is Not Enough to Relieve Fatigue: A Multicenter Randomized Controlled Trial.

William Jacot, Antoine Arnaud, Marta Jarlier, Claudia Lefeuvre-Plesse, Philippe Dalivoust, Pierre Senesse, Ahmed Azzedine, Olivier Tredan, Sophie Sadot-Lebouvier, Sébastien Mas and 11 more

Open access · goldAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 7 pooled it
1.3field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 7 syntheses or guidelines pooled it, 29 citations in OpenAlex.

  1. Pooled it
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  8. Trial
  9. The combined effect of physical exercise, pranayama, and diet on fatigue in adult cancer patients undergoing chemotherapy: a randomized controlled trial.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Trial
  10. Review
  11. Exercise Prescription in Cardio-Oncology.Journal of clinical medicine · 2025
    Review
  12. The effectiveness of exercise and/or nutritional interventions to improve the quality of life of women with breast cancer receiving radiation therapy: a scoping review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Article
  13. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 8 institutions in 1 country.

William JacotVal d'Aurelle Montpellier Cancer Institute (ICM), 208 Avenue des Apothicaires, Parc Euromédecine, CEDEX 5, 34298 Montpellier, France.ORCID 0000-0001-7834-061X
Antoine ArnaudSainte-Catherine Institute, 1750 Chemin Lavarin, 84000 Avignon, France.
Marta JarlierVal d'Aurelle Montpellier Cancer Institute (ICM), 208 Avenue des Apothicaires, Parc Euromédecine, CEDEX 5, 34298 Montpellier, France.
Claudia Lefeuvre-PlesseEugène Marquis Center, Rue de la Bataille Flandres-Dunkerque, CS 44229, 35042 Rennes, France.
Philippe DalivoustAmbroise Paré Hospital, 1 Rue de l'Eylau, 13006 Marseille, France.
Pierre SenesseVal d'Aurelle Montpellier Cancer Institute (ICM), 208 Avenue des Apothicaires, Parc Euromédecine, CEDEX 5, 34298 Montpellier, France.
Ahmed AzzedineMontélimar Hospital, Quartier Beausseret, BP 249-26, 26216 Montélimar, France.
Olivier TredanLéon Bérard Center, 28 Rue Laennec, 69008 Lyon, France.
Sophie Sadot-LebouvierRené Gauducheau Center, Boulevard Jacques Monod, 44805 Saint-Herblain, France.
Sébastien MasVal d'Aurelle Montpellier Cancer Institute (ICM), 208 Avenue des Apothicaires, Parc Euromédecine, CEDEX 5, 34298 Montpellier, France.
Marion CarayolIAPS Laboratory "Impact of Physical Activity on Health", University of Toulon, Avenue de l'Université, 83957 La Garde, France.
Jean-Pierre BleuseVal d'Aurelle Montpellier Cancer Institute (ICM), 208 Avenue des Apothicaires, Parc Euromédecine, CEDEX 5, 34298 Montpellier, France.
Sophie GourgouVal d'Aurelle Montpellier Cancer Institute (ICM), 208 Avenue des Apothicaires, Parc Euromédecine, CEDEX 5, 34298 Montpellier, France.
Chloé JaniszewskiVal d'Aurelle Montpellier Cancer Institute (ICM), 208 Avenue des Apothicaires, Parc Euromédecine, CEDEX 5, 34298 Montpellier, France.
Silene LaunayVal d'Aurelle Montpellier Cancer Institute (ICM), 208 Avenue des Apothicaires, Parc Euromédecine, CEDEX 5, 34298 Montpellier, France.
Véronique D'HondtVal d'Aurelle Montpellier Cancer Institute (ICM), 208 Avenue des Apothicaires, Parc Euromédecine, CEDEX 5, 34298 Montpellier, France.
Géraldine LauridantOscar Lambret Center, 3 Rue Frédéric Combemale, 59000 Lille, France.
Julien GrenierSainte-Catherine Institute, 1750 Chemin Lavarin, 84000 Avignon, France.
Gilles RomieuVal d'Aurelle Montpellier Cancer Institute (ICM), 208 Avenue des Apothicaires, Parc Euromédecine, CEDEX 5, 34298 Montpellier, France.
Gregory NinotVal d'Aurelle Montpellier Cancer Institute (ICM), 208 Avenue des Apothicaires, Parc Euromédecine, CEDEX 5, 34298 Montpellier, France.
Laurence VanlemmensOscar Lambret Center, 3 Rue Frédéric Combemale, 59000 Lille, France.
Institut de Recherche en Cancérologie de Montpellier · FRUniversité de Montpellier · FRCentre Oscar Lambret · FRInstitut Sainte Catherine · FRCentre Eugène Marquis · FRCentre Léon Bérard · FRHôpital Ambroise-Paré · FRUniversité de Toulon · FR

Funding

INCa-DGOS Grant SHP-ESF 2012-079Montpellier Cancer SIRIC INCa_Inserm_DGOS_12553
6 · The paper itself

Abstract

Supervised exercise dietary programs are recommended to relieve cancer-related fatigue and weight increase induced by adjuvant treatment of early breast cancer (EBC). As this recommendation lacks a high level of evidence, we designed a multicenter randomized trial to evaluate the impact of an Adapted Physical Activity Diet (APAD) education program on fatigue. We randomized 360 women with EBC who were receiving adjuvant chemotherapy and radiotherapy to APAD or usual care at eight French cancer institutions. Data were collected at baseline, end of chemotherapy, end of radiotherapy, and 6 months post-treatment. The primary endpoint was the general cancer-related fatigue score using the MFI-20 questionnaire. Fatigue correlated with the level of precariousness, but we found no significant difference between the two groups in terms of general fatigue (

Indexed as

HospitalsBreast NeoplasmsChemoradiotherapy, AdjuvantDiet TherapyExercise TherapyFatigueFemaleHealth EducationHumansNutritional Physiological PhenomenaOrganization and AdministrationProgram EvaluationQuality of LifeTreatment Outcomebreast cancerdieteducationexercisefatiguequality of lifeweight

Identifiers

PMID33050321
PMCPMC7600233
OpenAlexW3092459737

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.