Evidence map›Paper›PMID 33050316›Full record

ArticleNutrients2020

Beneficial Role of Replacing Dietary Saturated Fatty Acids with Polyunsaturated Fatty Acids in the Prevention of Sarcopenia: Findings from the NU-AGE Cohort.

Diego Montiel-Rojas, Aurelia Santoro, Andreas Nilsson, Claudio Franceschi, Miriam Capri, Alberto Bazzocchi, Giuseppe Battista, Lisette C P G M de Groot, Edith J M Feskens, Agnes A M Berendsen and 7 more

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 26 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 8 institutions in 7 countries.

Diego Montiel-RojasSchool of Health Sciences, Örebro University, 702 81 Örebro, Sweden.ORCID 0000-0003-3268-1544
Aurelia SantoroDepartment of Experimental, Diagnostic and Specialty Medicine, Alma Mater Studiorum, University of Bologna, 40138 Bologna, Italy.
Andreas NilssonSchool of Health Sciences, Örebro University, 702 81 Örebro, Sweden.ORCID 0000-0003-3793-335X
Claudio FranceschiDepartment of Experimental, Diagnostic and Specialty Medicine, Alma Mater Studiorum, University of Bologna, 40138 Bologna, Italy.
Miriam CapriDepartment of Experimental, Diagnostic and Specialty Medicine, Alma Mater Studiorum, University of Bologna, 40138 Bologna, Italy.
Alberto BazzocchiDiagnostic and Interventional Radiology, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, Italy.
Giuseppe BattistaDepartment of Experimental, Diagnostic and Specialty Medicine, Alma Mater Studiorum, University of Bologna, 40138 Bologna, Italy.ORCID 0000-0003-3639-3494
Lisette C P G M de GrootDepartment of Human Nutrition and Health, Wageningen University, 6708WE Wageningen, The Netherlands.ORCID 0000-0003-2778-2789
Edith J M FeskensDepartment of Human Nutrition and Health, Wageningen University, 6708WE Wageningen, The Netherlands.
Agnes A M BerendsenDepartment of Human Nutrition and Health, Wageningen University, 6708WE Wageningen, The Netherlands.
Agata Bialecka-DebekDepartment of Human Nutrition, Warsaw University of Life Sciences-SGGW, 02-776 Warsaw, Poland.ORCID 0000-0002-7823-7134
Olga SuralaDepartment of Human Nutrition, Warsaw University of Life Sciences-SGGW, 02-776 Warsaw, Poland.ORCID 0000-0003-0419-9435
Barbara PietruszkaDepartment of Human Nutrition, Warsaw University of Life Sciences-SGGW, 02-776 Warsaw, Poland.
Susan Fairweather-TaitNorwich Medical School, University of East Anglia, Norwich NR4 7TJ, UK.ORCID 0000-0002-1413-5569
Amy JenningsNorwich Medical School, University of East Anglia, Norwich NR4 7TJ, UK.
Frederic CapelUnité de Nutrition Humaine (UNH), Institut National de Recherche pour L'agriculture, L'alimentation et L'environnement (INRAE), Université Clermont Auvergne, CRNH Auvergne, 63000 Clermont-Ferrand, France.ORCID 0000-0002-0133-0277
Fawzi KadiSchool of Health Sciences, Örebro University, 702 81 Örebro, Sweden.
Örebro University · SEUniversity of Bologna · ITWageningen University & Research · NLWarsaw University of Life Sciences · PLUniversity of East Anglia · GBIstituto Ortopedico Rizzoli · ITN. I. Lobachevsky State University of Nizhny Novgorod · RUUniversité Clermont Auvergne · FR

Funding

Seventh Framework Programme 266486
6 · The paper itself

Abstract

Dietary fat subtypes may play an important role in the regulation of muscle mass and function during ageing. The aim of the present study was to determine the impact of isocaloric macronutrient substitutions, including different fat subtypes, on sarcopenia risk in older men and women, while accounting for physical activity (PA) and metabolic risk. A total of 986 participants, aged 65-79 years, completed a 7-day food record and wore an accelerometer for a week. A continuous sex-specific sarcopenia risk score (SRS), including skeletal muscle mass assessed by dual-energy X-ray absorptiometry (DXA) and handgrip strength, was derived. The impact of the isocaloric replacement of saturated fatty acids (SFAs) by either mono- (MUFAs) or poly-unsaturated (PUFAs) fatty acids on SRS was determined using regression analysis based on the whole sample and stratified by adherence to a recommended protein intake (1.1 g/BW). Isocaloric reduction of SFAs for the benefit of PUFAs was associated with a lower SRS in the whole population, and in those with a protein intake below 1.1 g/BW, after accounting for age, smoking habits, metabolic disturbances, and adherence to PA guidelines. The present study highlighted the potential of promoting healthy diets with optimised fat subtype distribution in the prevention of sarcopenia in older adults.

Indexed as

AgedCohort StudiesDietary Fats, UnsaturatedDietary ProteinsEatingExerciseFatty AcidsFatty Acids, UnsaturatedFemaleHand StrengthHumansMaleNutritional Physiological PhenomenaRecommended Dietary AllowancesRiskSarcopeniaDietary Fats, UnsaturatedDietary ProteinsFatty AcidsFatty Acids, Unsaturatedageingdietary fatsisocaloric substitutionmacronutrientsmetabolic syndromemuscle massmuscle strengthphysical activity

Identifiers

PMID33050316
PMCPMC7600824
OpenAlexW3092218583

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.