Evidence map›Paper›PMID 33050234›Full record

ArticleVaccines2020

Shortening the Lipid A Acyl Chains of

Jesús Arenas, Elder Pupo, Coen Phielix, Dionne David, Afshin Zariri, Alla Zamyatina, Jan Tommassen, Peter van der Ley

Open access · goldAbstract read
In one paragraph

Article in Vaccines, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 20 citations in OpenAlex.

  1. Engineering low-endotoxin lipid A in a double auxotrophFrontiers in cellular and infection microbiology · 2026
    Article
  2. Review
  3. LpxR and PagL expression in live attenuated auxotrophicFrontiers in cellular and infection microbiology · 2025
    Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Biosynthesis of the Inner Core ofInternational journal of molecular sciences · 2023
    Article
  9. Article
  10. Review
  11. Review
  12. Regulated Expression ofInternational journal of molecular sciences · 2022
    Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Jesús ArenasDepartment of Molecular Microbiology and Institute of Biomembranes, Utrecht University, 3584 CH Utrecht, The Netherlands.ORCID 0000-0002-8134-0693
Elder PupoInstitute for Translational Vaccinology (Intravacc), 3721 MA Bilthoven, The Netherlands.
Coen PhielixInstitute for Translational Vaccinology (Intravacc), 3721 MA Bilthoven, The Netherlands.
Dionne DavidInstitute for Translational Vaccinology (Intravacc), 3721 MA Bilthoven, The Netherlands.
Afshin ZaririInstitute for Translational Vaccinology (Intravacc), 3721 MA Bilthoven, The Netherlands.
Alla ZamyatinaDepartment of Chemistry, University of Natural Resources and Life Sciences, 1190 Vienna, Austria.
Jan TommassenDepartment of Molecular Microbiology and Institute of Biomembranes, Utrecht University, 3584 CH Utrecht, The Netherlands.
Peter van der LeyInstitute for Translational Vaccinology (Intravacc), 3721 MA Bilthoven, The Netherlands.
Intravacc (Netherlands) · NLUtrecht University · NLBOKU University · AT

Funding

Austrian Science Fund FWF P 28915Austrian Science Fund FWF P 32397
6 · The paper itself

Abstract

Whooping cough, or pertussis, is an acute respiratory infectious disease caused by the Gram-negative bacterium

Indexed as

Bordetella pertussisendotoxinlipid A engineeringLPSreactogenicitywhole-cell vaccine

Identifiers

PMID33050234
PMCPMC7712016
OpenAlexW3091984825

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.