ReviewAntioxidants (Basel, Switzerland)2020
The Universal Soldier: Enzymatic and Non-Enzymatic Antioxidant Functions of Serum Albumin.
Review in Antioxidants (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
48 citing papers in PubMed, 1 synthesis or guideline pooled it, 96 citations in OpenAlex.
- Associations of per- and polyfluoroalkyl substances, polychlorinated biphenyls, organochlorine pesticides, and polybrominated diphenyl ethers with oxidative stress markers: A systematic review and meta-analysis.Environmental research · 2023Pooled it
- Prognostic value of the uric acid-to-albumin ratio for mid-term all-cause mortality after carotid artery stenting.Postepy w kardiologii interwencyjnej = Advances in interventional cardiology · 2026Article
- Spectroscopic and calorimetric analysis of the interaction between human serum albumin and newly synthesized quinoline derivatives.Naunyn-Schmiedeberg's archives of pharmacology · 2026Article
- Human Serum Albumin as a Prodrug Carrier for Tumor Therapy: Mechanisms, Applications, and Future Perspectives.Pharmaceutics · 2026Review
- Serum Oxidative Status and Thiol-Disulfide Homeostasis in Late-Gestation Holstein Heifers with and Without a History of Mid-Gestation Transport.Veterinary sciences · 2026Article
- The red cell distribution width to albumin ratio (RAR) for predicting prognosis in spontaneous intracerebral hemorrhage: a retrospective cohort study using the MIMIC-IV database.Scientific reports · 2026Article
- Association of the C-reactive protein-albumin-lymphocyte index with heart failure prevalence and mortality risk in older adults with hypertension: A cohort study.The Journal of international medical research · 2026Article
- Association of the nutritional metabolic risk index with metabolic dysfunction-associated steatotic liver disease in a sub-plateau population.Frontiers in endocrinology · 2026Article
- Dynamic changes in nutritional parameters, inflammatory, and immune biomarkers during (chemo-) radiotherapy for head and neck cancer: a prospective longitudinal study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Article
- Oxidative Stress in the Pathophysiology of Chronic Venous Disease: An Overview.Antioxidants (Basel, Switzerland) · 2025Review
- Dissecting clinical features of COVID-19 in a cohort of 21,312 acute care patients.Communications medicine · 2025Article
- Antioxidant Properties of Albumin and Diseases Related to Obstetrics and Gynecology.Antioxidants (Basel, Switzerland) · 2025Review
- Association between advanced lung cancer inflammation index and all-cause and cause-specific mortality among asthma patients: a cohort study.Frontiers in nutrition · 2025Article
- Association Between the C-Reactive Protein-Albumin-Lymphocyte Index and Endometriosis: Insights from the 1999-2006 National Health and Nutrition Examination Survey.International journal of women's health · 2025Article
- Predictive value of uric acid to albumin ratio for carotid atherosclerosis in type 2 diabetes mellitus: A retrospective study.PloS one · 2025Article
- Serum total antioxidant status in dogs: Reference intervals and influence of multiple biological and analytical factors.Veterinary clinical pathology · 2024Article
- Antioxidant and Emulsifying Activity of the Exopolymer Produced byInternational journal of molecular sciences · 2024Article
- Oxidative stress and type 2 diabetes: the development and the pathogenesis, Jordanian cross-sectional study.European journal of medical research · 2024Article
- SARS-COV-2 ORF9b Dysregulate Fibrinogen and Albumin Genes in a Liver Cell Line.Reports of biochemistry & molecular biology · 2024Article
- The effect of Channa striata, Moringa oleifera, and Curcuma xanthorrhiza extract on accelerating recovery in a ventilated patient with hemorrhagic shock grade 3 due to prolonged retained placenta: a case report.Journal of medical case reports · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
Abstract
As a carrier of many biologically active compounds, blood is exposed to oxidants to a greater extent than the intracellular environment. Serum albumin plays a key role in antioxidant defence under both normal and oxidative stress conditions. This review evaluates data published in the literature and from our own research on the mechanisms of the enzymatic and non-enzymatic activities of albumin that determine its participation in redox modulation of plasma and intercellular fluid. For the first time, the results of numerous clinical, biochemical, spectroscopic and computational experiments devoted to the study of allosteric modulation of the functional properties of the protein associated with its participation in antioxidant defence are analysed. It has been concluded that it is fundamentally possible to regulate the antioxidant properties of albumin with various ligands, and the binding and/or enzymatic features of the protein by changing its redox status. The perspectives for using the antioxidant properties of albumin in practice are discussed.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.