Evidence map›Paper›PMID 33050170›Full record

ArticleMicroorganisms2020

Clinical Relevance of Antibiotic Susceptibility Profiles for Screening Gram-negative Microorganisms Resistant to Beta-Lactam Antibiotics.

Francisco Montiel-Riquelme, Elisabeth Calatrava-Hernández, Miguel Gutiérrez-Soto, Manuela Expósito-Ruiz, José María Navarro-Marí, José Gutiérrez-Fernández

Open access · goldAbstract read
In one paragraph

Article in Microorganisms, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.4field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Comprehensive antibiotic resistome comparison ofCurrent research in microbial sciences · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. [Infections in patients colonized with carbapenem-resistant Gram-negative bacteria in a medium Spanish city].Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2021
    Article
  7. Antimicrobial Resistance inAntibiotics (Basel, Switzerland) · 2021
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Francisco Montiel-RiquelmeDepartment of Microbiology, School of Medicine, University of Granada-ibs, 18012 Granada, Spain.ORCID 0000-0002-8259-5700
Elisabeth Calatrava-HernándezDepartment of Microbiology, Hospital Universitario Virgen de las Nieves-ibs, 18012 Granada, Spain.
Miguel Gutiérrez-SotoDepartment of Emergency, Hospital de la Agencia Sanitaria Alto Guadalquivir, 14550 Montilla, Spain.
Manuela Expósito-RuizDepartment of Investigation, Hospital Universitario Virgen de las Nieves, 18012 Granada, Spain.ORCID 0000-0003-2789-9442
José María Navarro-MaríDepartment of Microbiology, Hospital Universitario Virgen de las Nieves-ibs, 18012 Granada, Spain.
José Gutiérrez-FernándezDepartment of Microbiology, School of Medicine, University of Granada-ibs, 18012 Granada, Spain.ORCID 0000-0001-6146-9740
Hospital Universitario Virgen de las Nieves · ESUniversidad de Granada · ESHospital Alto Guadalquivir · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The increasing resistance to antibiotics is compromising the empirical treatment of infections caused by resistant bacteria. Rapid, efficient, and clinically applicable phenotypic methods are needed for their detection. This study examines the phenotypic behavior of β-lactam-resistant Gram-negative bacteria grown on ChromID ESBL medium with ertapenem, cefoxitin, and cefepime disks, reports on the coloration of colonies, and establishes a halo diameter breakpoint for the detection of carbapenemase-producing bacteria. We studied 186 β-lactam-resistant Gram-negative microorganisms (77 with extended spectrum beta lactamase (ESBL), 97 with carbapenemases, and 12 with AmpC β-lactamases (AmpC)). Susceptibility profiles of Gram-negative bacteria that produced ESBL, AmpC, and carbapenemases were similar to the expected profiles, with some differences in the response to cefepime of ESBL-producing microorganisms. Coloration values did not differ from those described by the manufacturer of ChromID ESBL medium. In the screening of carbapenemase production, inhibition halo diameter breakpoints for antibiotic resistance were 18 mm for

Indexed as

Acinetobacterbeta-lactam antibioticsEnterobacteralesPseudomonasresistance

Identifiers

PMID33050170
PMCPMC7601678
OpenAlexW3092143560

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.